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Keyword

epithelial sodium channel

Description: A membrane ion channel that enables sodium transport across epithelial cells and contributes to fluid and electrolyte balance.
Wikidata ID: wiki/Q424948
OpenAlex ID: keywords/enac
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
1994 · Cecilia M. Canessa, Laurent Schild, et al. · Nature · 1,961
Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel
1994 · Richard A. Shimkets, David G. Warnock, et al. · Cell · 1,260
Epithelial sodium channels: function, structure, and regulation
1997 · H. Garty, L. G. Palmer · Physiological Reviews · 1,155
CFTR as a cAMP-Dependent Regulator of Sodium Channels
1995 · M. Jackson Stutts, Cecilia M. Canessa, et al. · Science · 1,088
Epithelial Sodium Channel/Degenerin Family of Ion Channels: A Variety of Functions for a Shared Structure
2002 · Stephan Kellenberger, Laurent Schild · Physiological Reviews · 1,027
Epithelial sodium channel related to proteins involved in neurodegeneration
1993 · Cecilia M. Canessa, Jean-Daniel Horisberger, et al. · Nature · 920
Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice
1996 · Edith Hummler, Pierre Barker, et al. · Nature Genetics · 876
WW domains of Nedd4 bind to the proline‐rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.
1996 · O. Staub, S. Dho, et al. · The EMBO Journal · 851
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Amiloride: a molecular probe of sodium transport in tissues and cells
1982 · D. J. Benos · American Journal of Physiology-Cell Physiology · 840
Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
1996 · Sue S. Chang, Stefan Grunder, et al. · Nature Genetics · 814
Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome
1995 · Joni H. Hansson, Carol Nelson-Williams, et al. · Nature Genetics · 754
Epithelial sodium channel regulated by aldosterone-induced protein sgk
1999 · Sei-yu Chen, Aditi Bhargava, et al. · Proceedings of the National Academy of Sciences · 734
Aldosterone-mediated regulation of ENaC α, β, and γ subunit proteins in rat kidney
1999 · Shyama Masilamani, Gheun-Ho Kim, et al. · Journal of Clinical Investigation · 726
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Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination
1997 · O. Staub, I. Gautschi, et al. · The EMBO Journal · 699
The cells and peripheral representation of sodium taste in mice
2010 · Jayaram Chandrashekar, Christina Kuhn, et al. · Nature · 695
Lung Epithelial Fluid Transport and the Resolution of Pulmonary Edema
2002 · Michael A. Matthay, Hans G. Folkesson, et al. · Physiological Reviews · 670
Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
2005 · YouFei Guan, Chuanming Hao, et al. · Nature Medicine · 609
An epithelial serine protease activates the amiloride-sensitive sodium channel
1997 · Vronique Vallet, Ahmed Chraibi, et al. · Nature · 514
Management of Pulmonary Disease in Patients with Cystic Fibrosis
1996 · Bonnie W. Ramsey · New England Journal of Medicine · 502
Plasma sodium stiffens vascular endothelium and reduces nitric oxide release
2007 · Hans Oberleithner, Christoph Riethmüller, et al. · Proceedings of the National Academy of Sciences · 480
The Complex and Intriguing Lives of PIP2 with Ion Channels and Transporters
2001 · D. W. Hilgemann, S. Feng, et al. · Science Signaling · 463
Hypertension in Diabetes: An Update of Basic Mechanisms and Clinical Disease
2021 · Guanghong Jia, James R. Sowers · Hypertension · 430
Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I
1998 · David S. Geller, Juan Rodriguez-Soriano, et al. · Nature Genetics · 426
Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach
1996 · Dmitri Firsov, Laurent Schild, et al. · Proceedings of the National Academy of Sciences · 421
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel
1995 · Peter M. Snyder, Margaret P. Price, et al. · Cell · 410
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Works count: 7,238
Citation count: 179,300
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