Keyword

EphB2

Description: A receptor tyrosine kinase in the EphB family that binds ephrin ligands and participates in cell signaling, neural development, and cancer biology.

Primary topic: Axon Guidance and Neuronal Signaling (29%)

OpenAlex ID: keywords/ephb2

Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

2007 · Pascale N. Lacor, Maria C. Buniel, et al. · Journal of Neuroscience · 1,188

PDF

β-Catenin and TCF Mediate Cell Positioning in the Intestinal Epithelium by Controlling the Expression of EphB/EphrinB

2002 · Eduard Batlle, Jeffrey T. Henderson, et al. · Cell · 1,120

PDF

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1999 · R. H. Adams, G. A. Wilkinson, et al. · Genes & Development · 1,025

PDF

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

2011 · Anna Merlos-Suárez, Francisco M. Barriga, et al. · Cell stem cell · 934

PDF

Isolation and in vitro expansion of human colonic stem cells

2011 · Peter Jung, Toshiro Sato, et al. · Nature Medicine · 707

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1

2003 · Frank Kuhnert, Corrine R. Davis, et al. · Proceedings of the National Academy of Sciences · 636

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling

2004 · Juha-Pekka Himanen, Michael J Chumley, et al. · Nature Neuroscience · 453

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

2010 · Moustapha Cissé, Brian Halabisky, et al. · Nature · 431

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

1998 · E. Stein, A. A. Lane, et al. · Genes & Development · 424

PDF

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

2010 · Robert A. Johnson, Karen D. Wright, et al. · Nature · 367

Ephrin-B2 and EphB2 Regulation of Astrocyte-Meningeal Fibroblast Interactions in Response to Spinal Cord Lesions in Adult Rats

2003 · Liza Q. Bundesen, Tracy Aber Scheel, et al. · Journal of Neuroscience · 344

PDF

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

2012 · Lenka Mikasova, Pierre De Rossi, et al. · Brain · 342

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

1999 · Katja Brückner, Juan Pablo Labrador, et al. · Neuron · 342

PDF

Crystal structure of an Eph receptor–ephrin complex

2001 · Juha-Pekka Himanen, Kanagalaghatta R. Rajashankar, et al. · Nature · 339

Structural Basis for Autoinhibition of the EphB2 Receptor Tyrosine Kinase by the Unphosphorylated Juxtamembrane Region

2001 · Leanne E. Wybenga-Groot, Berivan Baskin, et al. · Cell · 338

PDF

Differential Gene Expression of Eph Receptors and Ephrins in Benign Human Tissues and Cancers

2004 · Christian Hafner, Gerd Schmitz, et al. · Clinical Chemistry · 323

The Receptor Tyrosine Kinase EphB2 Regulates NMDA-Dependent Synaptic Function

2001 · Jeffrey T Henderson, John Georgiou, et al. · Neuron · 320

PDF

Colorectal serrated adenocarcinoma

2006 · M J Mäkinen · Histopathology · 316

EphB/Syndecan-2 Signaling in Dendritic Spine Morphogenesis

2001 · Iryna M. Ethell, Fumitoshi Irie, et al. · Neuron · 309

PDF

Kinase-Independent Requirement of EphB2 Receptors in Hippocampal Synaptic Plasticity

2001 · Ilona C. Grunwald, Martin Korte, et al. · Neuron · 306

PDF

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus

2003 · Mark Henkemeyer, Olga S. Itkis, et al. · The Journal of Cell Biology · 302

PDF

EphB Forward Signaling Controls Directional Branch Extension and Arborization Required for Dorsal-Ventral Retinotopic Mapping

2002 · Robert Hindges, Todd McLaughlin, et al. · Neuron · 302

PDF

EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP

2002 · Fumitoshi Irie, Yu Yamaguchi · Nature Neuroscience · 286

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

1997 · Sacha J. Holland, Nicholas W. Gale, et al. · The EMBO Journal · 271

PDF

EphB–ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells

2007 · Carme Cortina, Sergio Palomo-Ponce, et al. · Nature Genetics · 269

Works count: 1,433

Citation count: 37,460