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Keyword

ERBB2

Description: ERBB2 is a human protein-coding gene that encodes the HER2 receptor, a cell-surface protein studied in cancer biology.
Wikidata ID: wiki/Q14877486
OpenAlex ID: keywords/erbb2
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 · Roger McLendon, Darrell Bigner, et al. · Nature · 7,724
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Untangling the ErbB signalling network
2001 · Yosef Yarden, Mark X. Sliwkowski · Nature Reviews Molecular Cell Biology · 6,965
Comprehensive molecular profiling of lung adenocarcinoma
2014 · Eric A. Collisson, Barry S. Taylor, et al. · Nature · 5,713
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Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
2010 · Richard A Morgan, James C Yang, et al. · Molecular Therapy · 2,536
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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
2003 · Jayanta Debnath, Senthil K. Muthuswamy, et al. · Methods · 2,000
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
2004 · Yoichi Nagata, Keng-Hsueh Lan, et al. · Cancer Cell · 1,858
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Integrated genomic characterization of oesophageal carcinoma
2017 · Nature · 1,828
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Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs
2014 · Mark G. Kris, Bruce E. Johnson, et al. · JAMA · 1,721
Proteogenomics connects somatic mutations to signalling in breast cancer
2016 · NCI CPTAC, Philipp Mertins, et al. · Nature · 1,668
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
2003 · Hyun-Soo Cho, Karen Mason, et al. · Nature · 1,613
ErbB‐2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
1997 · Diana Graus‐Porta, Roger R. Beerli, et al. · The EMBO Journal · 1,590
The ErbB/HER family of protein-tyrosine kinases and cancer
2013 · Robert Roskoski · Pharmacological Research · 1,356
The EGF receptor family as targets for cancer therapy
2000 · John Mendelsohn, Jose Baselga · Oncogene · 1,340
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
2006 · Koei Chin, Sandy DeVries, et al. · Cancer Cell · 1,317
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Multiple essential functions of neuregulin in development
1995 · Dirk Meyer, Carmen Birchmeier · Nature · 1,262
Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.
1992 · C T Guy, M A Webster, et al. · Proceedings of the National Academy of Sciences · 1,193
Novel anticancer targets: revisiting ERBB2 and discovering ERBB3
2009 · José Baselga, Sandra M. Swain · Nature reviews. Cancer · 1,142
A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)
2004 · Edgar R. Wood, Anne T. Truesdale, et al. · Cancer Research · 1,122
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
2004 · Matthew C Franklin, Kendall D Carey, et al. · Cancer Cell · 1,121
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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
2015 · Giulia Siravegna, Benedetta Mussolin, et al. · Nature Medicine · 1,085
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Letrozole Is More Effective Neoadjuvant Endocrine Therapy Than Tamoxifen for ErbB-1– and/or ErbB-2–Positive, Estrogen Receptor–Positive Primary Breast Cancer: Evidence From a Phase III Randomized Trial
2001 · Matthew J. Ellis, Andrew Coop, et al. · Journal of Clinical Oncology · 1,060
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A Hierarchical Network of Interreceptor Interactions Determines Signal Transduction by Neu Differentiation Factor/Neuregulin and Epidermal Growth Factor
1996 · Eldad Tzahar, Hadassa Waterman, et al. · Molecular and Cellular Biology · 1,037
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Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
2009 · Zachary T. Schafer, Alexandra R. Grassian, et al. · Nature · 1,031
erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells
1987 · Pier Paolo Di Fiore, Jacalyn H. Pierce, et al. · Science · 1,010
The biology of erbB-2/nue/HER-2 and its role in cancer
1994 · N Hynes · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 971
Works count: 10,960
Citation count: 345,300
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