Get started
Keyword

ErbB4

Description: ErbB4 is a receptor tyrosine kinase encoded by the ERBB4 gene that binds neuregulins and participates in cell signaling and development.
Wikidata ID: wiki/Q17917202
OpenAlex ID: keywords/erbb4
Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations
2013 · Lecia V. Sequist, James Chih-Hsin Yang, et al. · Journal of Clinical Oncology · 3,224
Neuregulin 1 and Susceptibility to Schizophrenia
2002 · Hreinn Stefansson, Hannes Petursson, et al. · The American Journal of Human Genetics · 1,683
PDF
ErbB‐2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
1997 · Diana Graus‐Porta, Roger R. Beerli, et al. · The EMBO Journal · 1,590
The ErbB/HER family of protein-tyrosine kinases and cancer
2013 · Robert Roskoski · Pharmacological Research · 1,356
Multiple essential functions of neuregulin in development
1995 · Dirk Meyer, Carmen Birchmeier · Nature · 1,262
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
1995 · Martin Gassmann, Franca Casagranda, et al. · Nature · 1,148
A Hierarchical Network of Interreceptor Interactions Determines Signal Transduction by Neu Differentiation Factor/Neuregulin and Epidermal Growth Factor
1996 · Eldad Tzahar, Hadassa Waterman, et al. · Molecular and Cellular Biology · 1,037
PDF
Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury
2009 · Kevin Bersell, Shima Arab, et al. · Cell · 1,034
PDF
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
2008 · Lin Mei, Wen-Cheng Xiong · Nature reviews. Neuroscience · 1,029
Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker
2012 · Flavio Solca, Goeran Dahl, et al. · Journal of Pharmacology and Experimental Therapeutics · 858
γ-Secretase Cleavage and Nuclear Localization of ErbB-4 Receptor Tyrosine Kinase
2001 · Chang-Yuan Ni, M. Paul Murphy, et al. · Science · 856
Endocytosis and intracellular trafficking of ErbBs
2008 · Alexander Sorkin, Lai Kuan Goh · Experimental Cell Research · 756
Phosphotyrosine interactome of the ErbB‐receptor kinase family
2005 · Waltraud X Schulze, Lei Deng, et al. · Molecular Systems Biology · 751
Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.
1993 · G D Plowman, J M Culouscou, et al. · Proceedings of the National Academy of Sciences · 713
ErbB‐2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.
1996 · D. Karunagaran, E. Tzahar, et al. · The EMBO Journal · 674
PDF
Integrated Profiling of MicroRNAs and mRNAs: MicroRNAs Located on Xq27.3 Associate with Clear Cell Renal Cell Carcinoma
2010 · Liang Zhou, Jiahao Chen, et al. · PLoS ONE · 642
PDF
The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors
2003 · Thomas P.J. Garrett, Neil M. McKern, et al. · Molecular Cell · 613
PDF
Expression of the HER1–4 family of receptor tyrosine kinases in breast cancer
2003 · Caroline J Witton, Jonathan R Reeves, et al. · The Journal of Pathology · 590
A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling
1994 · Kermit L. Carraway, Lewis C. Cantley · Cell · 587
Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia
2006 · Chang-Gyu Hahn, Hoau-Yan Wang, et al. · Nature Medicine · 563
The Distinctive Nature of HER2-Positive Breast Cancers
2005 · Harold J. Burstein · New England Journal of Medicine · 541
γ-Secretase, notch, Aβ and alzheimer's disease: Where do the presenilins fit in?
2002 · Sangram S. Sisodia, Peter H. St George-Hyslop · Nature reviews. Neuroscience · 512
Neuregulins Promote Survival and Growth of Cardiac Myocytes
1998 · You-yang Zhao, Douglas R. Sawyer, et al. · Journal of Biological Chemistry · 504
PDF
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy
2013 · Julie Halkein, Sebastien P. Tabruyn, et al. · Journal of Clinical Investigation · 499
PDF
Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling
2010 · Pietro Fazzari, Ana V. Paternain, et al. · Nature · 497
Works count: 4,267
Citation count: 135,500
Year
Topic
Type