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Keyword

esperamicin

Description: Esperamicin is a class of enediyne antibiotics studied for their potent antitumor activity and interactions with DNA.
OpenAlex ID: keywords/esperamicin
Chemistry and Biology of the Enediyne Anticancer Antibiotics
1991 · K. C. Nicolaou, W.‐M. Dai · Angewandte Chemie International Edition in English · 989
Esperamicins, a novel class of potent antitumor antibiotics. 3. Structures of esperamicins A1, A2, and A1b
1987 · Jerzy Golik, George Dubay, et al. · Journal of the American Chemical Society · 314
Chemie und Biologie von Endiin‐Cytostatica/Antibiotica
1991 · K. C. Nicolaou, W.‐M. Dai · Angewandte Chemie · 293
Cyclic conjugated enediynes related to calicheamicins and esperamicins: calculations, synthesis, and properties
1988 · K. C. Nicolaou, Y. Ogawa, et al. · Journal of the American Chemical Society · 288
Esperamicins, a novel class of potent antitumor antibiotics. 2. Structure of esperamicin X
1987 · Jerzy Golik, Jon Clardy, et al. · Journal of the American Chemical Society · 272
Biradical formation from acyclic conjugated eneyne-allene system related to neocarzinostatin and esperamicin-calichemicin
1989 · Ryu Nagata, Hidenori Yamanaka, et al. · Tetrahedron Letters · 230
Design of Enediyne Prodrugs
1995 · Martin E. Maier · Synlett · 148
Esperamicins, a novel class of potent antitumor antibiotics. I. Physico-chemical data and partial structure.
1985 · MASATAKA KONISHI, HIROAKI OHKUMA, et al. · The Journal of Antibiotics · 146
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One Pot Synthesis of Haloacetylenes from Trimethylsilylacetylenes
1994 · Toshio Nishikawa, Satoshi Shibuya, et al. · Synlett · 144
Enediyne antibiotics as antitumor agents
1995 · Donald B. Borders, Terrence W. Doyle · M. Dekker eBooks · 121
Esperamicins, a class of potent antitumor antibiotics: mechanism of action.
1989 · B H Long, J Golik, et al. · Proceedings of the National Academy of Sciences · 121
DNA cleavage by a synthetic mimic of the calicheamicin-esperamicin class of antibiotics
1988 · K. C. Nicolaou, Y. Ogawa, et al. · Journal of the American Chemical Society · 121
A continuous assay for DNA cleavage: The application of “break lights” to enediynes, iron-dependent agents, and nucleases
2000 · John B. Biggins, James R. Prudent, et al. · Proceedings of the National Academy of Sciences · 111
Synthesis of the bicyclic core of the esperamicin/calichemicin class of antitumor agents
1988 · Stuart L. Schreiber, Laura L. Kiessling · Journal of the American Chemical Society · 109
Abasic and Oxidized Abasic Site Reactivity in DNA: Enzyme Inhibition, Cross-Linking, and Nucleosome Catalyzed Reactions
2013 · Marc M. Greenberg · Accounts of Chemical Research · 107
Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model
2003 · Wen Liu, Joachim Ahlert, et al. · Proceedings of the National Academy of Sciences · 96
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Syntheses and transannular cyclizations of neocarzinostatin-chromophore and esperamicin-calichemicin analogs
1991 · Takayuki Doi, Takashi Takahashi · The Journal of Organic Chemistry · 88
The synthesis of the core trisaccharide of esperamicin: corroboration of the proposed structure for its rearrangement product and stabilization of the core trisaccharide domain
1991 · Randall L. Halcomb, Mark D. Wittman, et al. · Journal of the American Chemical Society · 83
The cyclization of calichemicin-esperamicin analogs: a predictive biradicaloid transition state
1989 · James P. Snyder · Journal of the American Chemical Society · 77
Nucleotide-specific cleavage and minor-groove interaction of DNA with esperamicin antitumor antibiotics.
1989 · Y Sugiura, Y Uesawa, et al. · Proceedings of the National Academy of Sciences · 74
A general strategy using η2co2(co)6 acetylene complexes for the synthesis of the enediyne antitumor agents esperamicin, calicheamicin, dy
1994 · Philip Magnus · Tetrahedron · 73
The esperamicin- calicheamicin aglycones: Ring closure of a simple strained system mediated by chromium(II)-nickel(II) salts
1991 · Cristophe Crévisy, Jean-Marie Beau · Tetrahedron Letters · 73
Coupled kinetic analysis of cleavage of DNA by esperamicin and calicheamicin
1991 · Hiroko Kishikawa, Ying Ping Jiang, et al. · Journal of the American Chemical Society · 68
Concise route to the calichemicin-esperamicin series: the crystal structure of an aglycone prototype
1988 · Samuel J. Danishefsky, Nathan B. Mantlo, et al. · Journal of the American Chemical Society · 65
Studies Related to the Carbohydrate Sectors of Esperamicin and Calicheamicin: Definition of the Stability Limits of the Esperamicin Domain and Fashioning of a Glycosyl Donor from the Calicheamicin Domain
1995 · Randall L. Halcomb, Serge H. Boyer, et al. · Journal of the American Chemical Society · 64
Works count: 134
Citation count: 5,132
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