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factor XI
Description:
Coagulation factor XI is a blood plasma protein that participates in the intrinsic pathway of blood coagulation.
Primary topic:
Coagulation, Bradykinin, Polyphosphates, and Angioedema (38%)
Related topics:
Coagulation, Bradykinin, Polyphosphates, and Angioedema (38%),
Blood Coagulation and Thrombosis Mechanisms (24%),
Hemophilia Treatment and Research (9%)
Wikidata ID:
wiki/Q419531
OpenAlex ID:
keywords/factor-xi
An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier
1964
·
R. G. MACFARLANE
·
Nature
·
1,119
Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces
1980
·
L Vroman
, AL Adams
, et al.
·
Blood
·
782
High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis
2000
·
Joost C.M. Meijers
, Winnie L.H. Tekelenburg
, et al.
·
New England Journal of Medicine
·
700
Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis
2014
·
Harry R. Büller
, Claudette Bethune
, et al.
·
New England Journal of Medicine
·
630
PDF
Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation
2007
·
Christian Kannemeier
, Aya Shibamiya
, et al.
·
Proceedings of the National Academy of Sciences
·
535
PDF
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
2006
·
Christoph Kleinschnitz
, Guido Stoll
, et al.
·
The Journal of Experimental Medicine
·
454
PDF
Activation of human blood coagulation factor XI independent of factor XII.
1991
·
K Naito
, K Fujikawa
·
Journal of Biological Chemistry
·
407
New Hemophilia-like Disease Caused by Deficiency of a Third Plasma Thromboplastin Factor.
1953
·
R. L. Rosenthal
, O. H. Dreskin
, et al.
·
Experimental Biology and Medicine
·
402
Activation of Hageman Factor in Solid and Fluid Phases
1973
·
C. G. Cochrane
, S. D. Revak
, et al.
·
The Journal of Experimental Medicine
·
347
Intrinsic Pathway of Coagulation and Arterial Thrombosis
2007
·
David Gailani
, Thomas Renné
·
Arteriosclerosis Thrombosis and Vascular Biology
·
303
Contact activation of blood-plasma coagulation
2009
·
Erwin A. Vogler
, Christopher A. Siedlecki
·
Biomaterials
·
299
Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis
1995
·
PA von dem Borne
, JC Meijers
, et al.
·
Blood
·
292
Genetics of venous thrombosis
2009
·
F.R. ROSENDAAL
, P.H. REITSMA
·
Journal of Thrombosis and Haemostasis
·
291
Association of factor XI and high molecular weight kininogen in human plasma.
1977
·
R E Thompson
, R Mandle
, et al.
·
Journal of Clinical Investigation
·
279
PDF
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
1993
·
R A Pixley
, R De La Cadena
, et al.
·
Journal of Clinical Investigation
·
278
PDF
Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease
2009
·
E. J. van Beers
, M. C.L. Schaap
, et al.
·
Haematologica
·
272
PDF
Tissue Factor Pathway Inhibitor and the Revised Theory of Coagulation
1995
·
George J. Broze
·
Annual Review of Medicine
·
272
Microparticles from Patients with Multiple Organ Dysfunction Syndrome and Sepsis Support Coagulation through Multiple Mechanisms
2001
·
Karin Joop
, René Berckmans
, et al.
·
Thrombosis and Haemostasis
·
253
Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein
1986
·
Kazuo Fujikawa
, Dominic W. Chung
, et al.
·
Biochemistry
·
250
Misfolded proteins activate Factor XII in humans, leading to kallikrein formation without initiating coagulation
2008
·
Coen Maas
, José W.P. Govers-Riemslag
, et al.
·
Journal of Clinical Investigation
·
243
Levels of intrinsic coagulation factors and the risk of myocardial infarction among men: opposite and synergistic effects of factors XI and XII
2006
·
Carine J. M. Doggen
, Frits R. Rosendaal
, et al.
·
Blood
·
241
Intrinsic Pathway of Coagulation and Thrombosis
2019
·
Steven P. Grover
, Nigel Mackman
·
Arteriosclerosis Thrombosis and Vascular Biology
·
240
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment
2008
·
Guido Stoll
, Christoph Kleinschnitz
, et al.
·
Blood
·
237
PDF
A model for the tissue factor pathway to thrombin. I. An empirical study.
1994
·
J.H. Lawson
, M. Kalafatis
, et al.
·
Journal of Biological Chemistry
·
237
PDF
Dual role of collagen in factor XII–dependent thrombus formation
2009
·
Paola E. J. van der Meijden
, Imke C. A. Munnix
, et al.
·
Blood
·
235
PDF
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Works count:
2,315
Citation count:
51,170
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