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Keyword

FAPI-46

Description: FAPI-46 is a fibroblast activation protein-targeting inhibitor developed for radiolabeled imaging and radionuclide therapy in oncology.
OpenAlex ID: keywords/fapi-46
Development of Fibroblast Activation Protein–Targeted Radiotracers with Improved Tumor Retention
2019 · Anastasia Loktev, Thomas Lindner, et al. · Journal of Nuclear Medicine · 554
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Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy
2022 · Dirk Zboralski, Aileen Hoehne, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 286
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Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies
2023 · Bastiaan M. Privé, Mohamed A. Boussihmad, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 199
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Fibroblast activation protein targeted therapy using [177Lu]FAPI-46 compared with [225Ac]FAPI-46 in a pancreatic cancer model
2021 · Yuwei Liu, Tadashi Watabe, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 189
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Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of 68 Ga-Labeled FAPI Dimer
2021 · Liang Zhao, Bo Niu, et al. · Journal of Nuclear Medicine · 169
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Fibroblast Activation Protein–Specific PET/CT Imaging in Fibrotic Interstitial Lung Diseases and Lung Cancer: A Translational Exploratory Study
2021 · Manuel Röhrich, Dominik Leitz, et al. · Journal of Nuclear Medicine · 169
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Pitfalls and Common Findings in 68 Ga-FAPI PET: A Pictorial Analysis
2021 · Lukas Kessler, Justin Ferdinandus, et al. · Journal of Nuclear Medicine · 121
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Initial clinical experience with 90 Y-FAPI-46 radioligand therapy for advanced stage solid tumors: a case series of nine patients
2021 · Justin Ferdinandus, Pedro Fragoso Costa, et al. · Journal of Nuclear Medicine · 120
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Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy
2023 · Yizhen Pang, Liang Zhao, et al. · Journal of Nuclear Medicine · 119
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Non-oncologic incidental uptake on FAPI PET/CT imaging
2022 · Masatoshi Hotta, Angela C Rieger, et al. · British Journal of Radiology · 107
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[153Sm]Samarium-labeled FAPI-46 radioligand therapy in a patient with lung metastases of a sarcoma
2021 · Clemens Kratochwil, Frederik L. Giesel, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 100
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Head-to-head comparison of different classes of FAP radioligands designed to increase tumor residence time: monomer, dimer, albumin binders, and small molecules vs peptides
2023 · Jacopo Millul, Lennart Koepke, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 98
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Simultaneous FAPI PET/MRI Targeting the Fibroblast-Activation Protein for Breast Cancer
2021 · Philipp Backhaus, Matthias C. Burg, et al. · Radiology · 97
Equivalent tumor detection for early and late FAPI-46 PET acquisition
2021 · J. Ferdinandus, L. Kessler, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 69
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Development of Fibroblast Activation Protein Inhibitor-Based Dimeric Radiotracers with Improved Tumor Retention and Antitumor Efficacy
2022 · Liang Zhao, Jianhao Chen, et al. · Molecular Pharmaceutics · 52
Two Tumors, One Target
2021 · Hendrik Rathke, Stefan Fuxius, et al. · Clinical Nuclear Medicine · 42
177Lu-FAPI Therapy in a Patient With End-Stage Metastatic Pancreatic Adenocarcinoma
2022 · Fatemeh Kaghazchi, Ramin Akbarian Aghdam, et al. · Clinical Nuclear Medicine · 38
Clinically Applicable Cyclotron-Produced Gallium-68 Gives High-Yield Radiolabeling of DOTA-Based Tracers
2021 · Emma Jussing, Stefan Milton, et al. · Biomolecules · 33
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Fibroblast Activation Protein α–Directed Imaging and Therapy of Solitary Fibrous Tumor
2024 · Rainer Hamacher, Kim M. Pabst, et al. · Journal of Nuclear Medicine · 32
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Fibroblast Activation Protein Inhibitor Theranostics
2023 · Yuriko Mori, Clemens Kratochwil, et al. · PET Clinics · 32
Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013
2024 · Yue Tan, Jian Li, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 27
[68Ga]/[90Y]FAPI-46: Automated production and analytical validation of a theranostic pair
2022 · M. Nader, D.F. Valla, et al. · Nuclear Medicine and Biology · 27
Fibroblast activation protein inhibitor-positron emission tomography in aortitis: fibroblast pathology in active inflammation and remission
2024 · Manuel Röhrich, Juan J Rosales, et al. · Lara D. Veeken · 26
Synthesis and Preclinical Evaluation of Novel 99mTc-Labeled FAPI-46 Derivatives with Significant Tumor Uptake and Improved Tumor-to-Nontarget Ratios
2024 · Qing Ruan, Dajie Ding, et al. · Journal of Medicinal Chemistry · 24
Subclass Analysis of Malignant, Inflammatory and Degenerative Pathologies Based on Multiple Timepoint FAPI-PET Acquisitions Using FAPI-02, FAPI-46 and FAPI-74
2022 · Frederik M. Glatting, Jorge Hoppner, et al. · Cancers · 24
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Works count: 168
Citation count: 3,116
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