Get started
Keyword

FGF19

Description: Fibroblast growth factor 19, a signaling protein involved in bile acid regulation, metabolism, and developmental processes.
OpenAlex ID: keywords/fgf19
The FGF family: biology, pathophysiology and therapy
2009 · Andrew Beenken, Moosa Mohammadi · Nature Reviews Drug Discovery · 1,938
Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
2013 · Sunder Mudaliar, Robert R. Henry, et al. · Gastroenterology · 929
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
2000 · Tetsuya Nishimura, Yuhki Nakatake, et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 845
Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21
2007 · Hiroshi Kurosu, Mihwa Choi, et al. · Journal of Biological Chemistry · 746
PDF
Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD
2017 · Na Jiao, Susan S Baker, et al. · Gut · 735
The Klotho proteins in health and disease
2018 · Makoto Kuro-o · Nature Reviews Nephrology · 700
Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse
2010 · Klementina Fon Tacer, Angie L. Bookout, et al. · Molecular Endocrinology · 700
PDF
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
2003 · Jason A. Holt, Guizhen Luo, et al. · Genes & Development · 697
PDF
Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells
2015 · Keiko Muguruma, Ayaka Nishiyama, et al. · Cell Reports · 690
PDF
The Worldwide Incidence and Prevalence of Inflammatory Bowel Disease in the 21st Century: A Systematic Review of Population-Based Studies
2017 · Siew C. Ng, Hai Yun Shi, et al. · Gastroenterology · 675
FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis
2011 · Serkan Kir, Sara A. Beddow, et al. · Science · 636
Fibroblast Growth Factor 19 Increases Metabolic Rate and Reverses Dietary and Leptin-Deficient Diabetes
2004 · Ling Fu, Linu M. John, et al. · Endocrinology · 579
Transgenic Mice Expressing Human Fibroblast Growth Factor-19 Display Increased Metabolic Rate and Decreased Adiposity
2002 · Elizabeth Tomlinson, Ling Fu, et al. · Endocrinology · 575
PDF
Identification of a Novel Fibroblast Growth Factor, FGF-23, Preferentially Expressed in the Ventrolateral Thalamic Nucleus of the Brain
2000 · Tetsuo Yamashita, Masazumi Yoshioka, et al. · Biochemical and Biophysical Research Communications · 555
Molecular Insights into the Klotho-Dependent, Endocrine Mode of Action of Fibroblast Growth Factor 19 Subfamily Members
2007 · Regina Goetz, Andrew Beenken, et al. · Molecular and Cellular Biology · 545
Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice
2012 · Bo Kong, Li Wang, et al. · Hepatology · 456
Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening
2011 · Eric T. Sawey, Maia Chanrion, et al. · Cancer Cell · 436
PDF
Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23
2015 · Chiara Degirolamo, Carlo Sabbà, et al. · Nature Reviews Drug Discovery · 422
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α‐hydroxylase gene expression†
2008 · Kwang‐Hoon Song, Tiangang Li, et al. · Hepatology · 414
PDF
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
2006 · T. LUNDÅSEN, C. GÄLMAN, et al. · Journal of Internal Medicine · 406
PDF
Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease
2016 · Marialena Mouzaki, Alice Y. Wang, et al. · PLoS ONE · 385
PDF
The Role of Bile After Roux-en-Y Gastric Bypass in Promoting Weight Loss and Improving Glycaemic Control
2012 · Dimitri J. Pournaras, Clare Glicksman, et al. · Endocrinology · 383
PDF
Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice
2019 · Yunhuan Liu, Kefei Chen, et al. · Hepatology · 364
PDF
A Mouse Model of Hepatocellular Carcinoma
2002 · Katrina Nicholes, Susan Guillet, et al. · American Journal Of Pathology · 358
FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor
2012 · Vito Guagnano, Audrey Kauffmann, et al. · Cancer Discovery · 347
Works count: 2,317
Citation count: 65,740
Year
Topic
Type