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Keyword

FGFR2

Description: FGFR2 is a human protein-coding gene that encodes fibroblast growth factor receptor 2, a receptor involved in cell signaling and development.
Wikidata ID: wiki/Q14911644
OpenAlex ID: keywords/fgfr2
Genome-wide association study identifies novel breast cancer susceptibility loci
2007 · Douglas F. Easton, Karen A. Pooley, et al. · Nature · 2,320
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A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007 · David J Hunter, Peter Kraft, et al. · Nature Genetics · 1,481
Regulation of Alternative Splicing by Histone Modifications
2010 · Reini F. Luco, Qun Pan, et al. · Science · 1,109
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
2009 · Adam J Bass, Hideo Watanabe, et al. · Nature Genetics · 945
Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome
1995 · Andrew O.M. Wilkie, Sarah F. Slaney, et al. · Nature Genetics · 935
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
2000 · Laurence De Moerlooze, Bradley Spencer-Dene, et al. · Development · 864
A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration
2006 · Alexandra Lepilina, Ashley N. Coon, et al. · Cell · 833
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Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2
2019 · Toshihisa Komori · International Journal of Molecular Sciences · 825
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Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst
2010 · Guoji Guo, Mikael Huss, et al. · Developmental Cell · 815
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The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing
2015 · Teresa Helsten, Sheryl Elkin, et al. · Clinical Cancer Research · 811
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Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome
1994 · William Reardon, Robin M. Winter, et al. · Nature Genetics · 758
Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin
2000 · Luca Pellegrini, David F. Burke, et al. · Nature · 704
In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis
2002 · Ichiro Sekiya, Jussi T. Vuoristo, et al. · Proceedings of the National Academy of Sciences · 649
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
1998 · Esther Arman, Rebecca Haffner-Krausz, et al. · Proceedings of the National Academy of Sciences · 617
ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing
2009 · Claude C. Warzecha, Trey K. Sato, et al. · Molecular Cell · 579
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Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
1998 · Xiaoling Xu, Michael Weinstein, et al. · Development · 553
Developmental Localization of the Splicing Alternatives of Fibroblast Growth Factor Receptor-2 (FGFR2)
1993 · Avi Orr-Urtreger, Mark T. Bedford, et al. · Developmental Biology · 548
Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse
1992 · K. G. Peters, S. Werner, et al. · Development · 543
Craniosynostosis: genes and mechanisms
1997 · A. Wilkie · Human Molecular Genetics · 529
AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family
2012 · Paul R. Gavine, Lorraine Mooney, et al. · Cancer Research · 501
Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies
2005 · Gillian M. Morriss‐Kay, Andrew O. M. Wilkie · Journal of Anatomy · 485
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Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase
2011 · Vito Guagnano, Pascal Furet, et al. · Journal of Medicinal Chemistry · 478
Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18
2002 · Zhonghao Liu, Jingsong Xu, et al. · Genes & Development · 475
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Diverse alterations associated with resistance to KRAS(G12C) inhibition
2021 · Yulei Zhao, Yonina R. Murciano-Goroff, et al. · Nature · 473
Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2
1994 · Ethylin Wang Jabs, Xiang Li, et al. · Nature Genetics · 468
Works count: 5,434
Citation count: 132,000
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