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FGFR2b
Description:
FGFR2b is an epithelial splice isoform of fibroblast growth factor receptor 2 involved in growth factor signaling and cellular development.
Primary topic:
Fibroblast Growth Factor Research (32%)
Related topics:
Fibroblast Growth Factor Research (32%),
Gastric Cancer Management and Outcomes (17%)
OpenAlex ID:
keywords/fgfr2b
FGF10 Acts as a Major Ligand for FGF Receptor 2 IIIb in Mouse Multi-Organ Development
2000
·
Hideyo Ohuchi
, Yukiko Hori
, et al.
·
Biochemical and Biophysical Research Communications
·
636
Localization of Putative Stem Cells in Dental Epithelium and Their Association with Notch and Fgf Signaling
1999
·
Hidemitsu Harada
, Päivi Kettunen
, et al.
·
The Journal of Cell Biology
·
517
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate
2004
·
Ritva Rice
, Bradley Spencer-Dene
, et al.
·
Journal of Clinical Investigation
·
364
PDF
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
2006
·
Johanna Laurikkala
, Marja L. Mikkola
, et al.
·
Development
·
265
FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis
2005
·
Zachary Steinberg
, Christopher Myers
, et al.
·
Development
·
263
PDF
Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo
2002
·
Arnaud André Mailleux
, Bradley Spencer-Dene
, et al.
·
Development
·
255
Bemarituzumab in patients with FGFR2b-selected gastric or gastro-oesophageal junction adenocarcinoma (FIGHT): a randomised, double-blind, placebo-controlled, phase 2 study
2022
·
Zev A Wainberg
, Peter C Enzinger
, et al.
·
The Lancet Oncology
·
231
Expression and function of FGF10 in mammalian inner ear development
2003
·
Sarah Pauley
, Tracy J. Wright
, et al.
·
Developmental Dynamics
·
229
PDF
Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells
2003
·
Alan Hart
, Stella Papadopoulou
, et al.
·
Developmental Dynamics
·
217
FGF signalling in craniofacial development and developmental disorders
2006
·
X Nie
, K Luukko
, et al.
·
Oral Diseases
·
195
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors
2003
·
Brian K. Yeh
, Makoto Igarashi
, et al.
·
Proceedings of the National Academy of Sciences
·
192
PDF
miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution
2009
·
Gianni Carraro
, Ahmed El-Hashash
, et al.
·
Developmental Biology
·
172
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
2007
·
Vaishali N. Patel
, Sarah M. Knox
, et al.
·
Development
·
157
PDF
Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
2004
·
O. A. Ibrahimi
·
Human Molecular Genetics
·
154
Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
2013
·
Chiara Francavilla
, Kristoffer T.G. Rigbolt
, et al.
·
Molecular Cell
·
146
PDF
Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia
2005
·
Anne Goriely
, Gilean A. T. McVean
, et al.
·
Proceedings of the National Academy of Sciences
·
146
PDF
Cancer genomics and genetics of FGFR2 (Review)
1992
·
Masaru Katoh
·
International Journal of Oncology
·
146
PDF
FGFR2-related pathogenesis and FGFR2-targeted therapeutics (Review)
2009
·
Katoh
·
International Journal of Molecular Medicine
·
139
PDF
Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via β-catenin activation
2007
·
Tove Berg
, Bart C. Rountree
, et al.
·
Hepatology
·
138
PDF
The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development
2007
·
Richard Grose
, Vera Fantl
, et al.
·
The EMBO Journal
·
126
Heparan sulfate–FGF10 interactions during lung morphogenesis
2003
·
Konstantin I Izvolsky
, Deana Shoykhet
, et al.
·
Developmental Biology
·
126
PDF
Expression and Function of Fibroblast Growth Factor 10 and Its Receptor, Fibroblast Growth Factor Receptor 2B, in Bovine Follicles1
2007
·
J. Buratini
, M.G.L. Pinto
, et al.
·
Biology of Reproduction
·
124
PDF
Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis
2015
·
BreAnne MacKenzie
, Martina Korfei
, et al.
·
Respiratory Research
·
123
PDF
Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling
2008
·
Sara Parsa
, Suresh K. Ramasamy
, et al.
·
Developmental Biology
·
123
PDF
Combined KIT and FGFR2b Signaling Regulates Epithelial Progenitor Expansion during Organogenesis
2013
·
Isabelle M.A. Lombaert
, Shaun R. Abrams
, et al.
·
Stem Cell Reports
·
119
PDF
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Works count:
403
Citation count:
10,680
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