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Keyword

fibrates

Description: A class of lipid-modifying drugs used mainly to lower triglycerides and improve blood lipid profiles in treating dyslipidemia.
Wikidata ID: wiki/Q424744
OpenAlex ID: keywords/fibrates
Gemfibrozil for the Secondary Prevention of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein Cholesterol
1999 · Hanna Bloomfield Rubins, Sander J. Robins, et al. · New England Journal of Medicine · 3,453
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Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
2005 · ‡ · The Lancet · 3,300
The Mechanisms of Action of PPARs
2002 · Joel Berger, David E. Moller · Annual Review of Medicine · 2,656
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
1997 · Steven A. Kliewer, Scott S. Sundseth, et al. · Proceedings of the National Academy of Sciences · 2,164
AHA/ACC Guidelines for Secondary Prevention for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2006 Update
2006 · Sidney C. Smith, Jerilyn Allen, et al. · Circulation · 2,105
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Roles of PPARs in health and disease
2000 · Sander Kersten, Béatrice Desvergne, et al. · Nature · 1,954
Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism
1998 · Bart Staels, Jean Dallongeville, et al. · Circulation · 1,786
Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients With Acute Coronary Syndromes
2003 · Steven E. Nissen, Taro Tsunoda, et al. · JAMA · 1,709
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EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis
2017 · Gideon M. Hirschfield, Ulrich Beuers, et al. · Journal of Hepatology · 1,481
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Genetically Elevated Lipoprotein(a) and Increased Risk of Myocardial Infarction
2009 · Pia R. Kamstrup · JAMA · 1,357
Secondary Prevention by Raising HDL Cholesterol and Reducing Triglycerides in Patients With Coronary Artery Disease
2000 · Circulation · 1,278
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
2011 · M. John Chapman, Henry N. Ginsberg, et al. · European Heart Journal · 1,224
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Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
1996 · K Schoonjans, B Staels, et al. · Journal of Lipid Research · 1,216
Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review
2014 · Bogna Grygiel-Górniak · Nutrition Journal · 1,201
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PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.
1996 · K. Schoonjans, J. Peinado‐Onsurbe, et al. · The EMBO Journal · 1,173
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Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors
1999 · H.Eric Xu, Millard H Lambert, et al. · Molecular Cell · 1,169
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Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1
1999 · Philippe Delerive, Karolien De Bosscher, et al. · Journal of Biological Chemistry · 1,088
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The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
1996 · Kristina Schoonjans, Bart Staels, et al. · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1,047
Peroxisome Proliferator-Activated Receptor Alpha Target Genes
2010 · Maryam Rakhshandehroo, Bianca Knoch, et al. · PPAR Research · 1,017
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Cardiac fibroblasts: At the heart of myocardial remodeling
2009 · Karen E. Porter, Neil A. Turner · Pharmacology & Therapeutics · 1,010
International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors
2006 · Liliane Michalik, Johan Auwerx, et al. · Pharmacological Reviews · 1,001
Sorting out the roles of PPAR in energy metabolism and vascular homeostasis
2006 · P. Lefebvre · Journal of Clinical Investigation · 960
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Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
2000 · G. Chinetti, J.-C. Fruchart, et al. · Inflammation Research · 954
PPAR control of metabolism and cardiovascular functions
2021 · David Montaigne, Laura Butruille, et al. · Nature Reviews Cardiology · 945
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Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis
2010 · Min Jun, Celine Foote, et al. · The Lancet · 926
Works count: 7,782
Citation count: 203,400
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