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formalin test
Description:
An animal pain assay in which formalin is injected to provoke measurable nociceptive behaviors and evaluate analgesic effects.
Primary topic:
Pain Mechanisms and Treatments (46%)
Related topics:
Pain Mechanisms and Treatments (46%),
Phytochemistry Medicinal Plant Applications (10%),
Medicinal Plant Research (9%)
OpenAlex ID:
keywords/formalin-test
The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats
1977
·
David Dubuisson
, Stephen G. Dennis
·
Pain
·
2,527
The formalin test: an evaluation of the method
1992
·
Arne Tjølsen
, Odd-Geir Berge
, et al.
·
Pain
·
2,429
The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
1987
·
Steinar Hunskaar
, Kjell Hole
·
Pain
·
2,187
Opiates and endogenous opioid peptides
1977
·
John S. Kelly
, Ray Dingledine
·
Trends in Biochemical Sciences
·
1,282
Modified formalin test: characteristic biphasic pain response
1989
·
Manabu Shibata
, Tsuyako Ohkubo
, et al.
·
Pain
·
954
Formalin test in mice, a useful technique for evaluating mild analgesics
1985
·
Steinar Hunskaar
, Ole Bernt Fasmer
, et al.
·
Journal of Neuroscience Methods
·
821
Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat.
1992
·
A B Malmberg
, T L Yaksh
·
Journal of Pharmacology and Experimental Therapeutics
·
643
Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2
2003
·
Catherine Abbadie
, Jill A. Lindia
, et al.
·
Proceedings of the National Academy of Sciences
·
591
PDF
The formalin test: scoring properties of the first and second phases of the pain response in rats
1995
·
Frances V. Abbott
, Keith B.J. Franklin
, et al.
·
Pain
·
587
Review of a Proposed Mechanism for the Antinociceptive Action of Botulinum Toxin Type A
2005
·
K.R. Aoki
·
NeuroToxicology
·
550
Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin
1987
·
Anthony H. Dickenson
, Ann F. Sullivan
·
Pain
·
536
Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection
1990
·
Terence J. Coderre
, Anthony L. Vaccarino
, et al.
·
Brain Research
·
532
Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord
1990
·
RW Presley
, D Menetrey
, et al.
·
Journal of Neuroscience
·
528
PDF
The phorbol ester receptor: a phospholipid-regulated protein kinase
1985
·
Curtis L. Ashendel
·
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes
·
515
Descending control of persistent pain: inhibitory or facilitatory?
2004
·
Horacio Vanegas
, Hans-Georg Schaible
·
Brain Research Reviews
·
509
Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils
2000
·
F. A. Santos
, V. S. N. Rao
·
Phytotherapy Research
·
497
l ‐NG‐nitro arginine methyl ester exhibits antinociceptive activity in the mouse
1991
·
P.K. Moore
, A.O. Oluyomi
, et al.
·
British Journal of Pharmacology
·
471
PDF
Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity
1996
·
S. Puig
, L. S. Sorkin
·
Pain
·
469
Evidence for spinalN-methyl-d-aspartate receptor involvement in prolonged chemical nociception in the rat
1990
·
Jane E. Haley
, Ann F. Sullivan
, et al.
·
Brain Research
·
460
Characterization of the novel nitric oxide synthase inhibitor 7‐nitro indazole and related indazoles: antinociceptive and cardiovascular effects
1993
·
P.K. Moore
, P. Wallace
, et al.
·
British Journal of Pharmacology
·
459
PDF
Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic pain
1993
·
C. Courteix
, A. Eschalier
, et al.
·
Pain
·
453
Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice
1999
·
Yanxin Zhu
, Michael A. King
, et al.
·
Neuron
·
430
PDF
Pharmacological properties of a potent and selective nonpeptide substance P antagonist.
1991
·
C Garret
, A Carruette
, et al.
·
Proceedings of the National Academy of Sciences
·
427
7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure
1993
·
P.K. Moore
, R.C. Babbedge
, et al.
·
British Journal of Pharmacology
·
424
PDF
The formalin test in mice: effect of formalin concentration
1990
·
Jan Henrik Rosland
, Arne Tjølsen
, et al.
·
Pain
·
399
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Works count:
6,390
Citation count:
159,000
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