Keyword

Foxp3

Description: A transcription factor that regulates immune-cell development and function, especially the differentiation and suppressive activity of regulatory T cells.

Primary topic: T-cell and B-cell Immunology (35%)

Related topic: T-cell and B-cell Immunology (35%)

OpenAlex ID: keywords/foxp3

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 · Shohei Hori, Takashi Nomura, et al. · Science · 8,189

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 · Jason D. Fontenot, Marc A. Gavin, et al. · Nature Immunology · 7,735

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

2006 · Estelle Bettelli, Yijun Carrier, et al. · Nature · 6,987

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

2013 · Yukihiro Furusawa, Yuuki Obata, et al. · Nature · 5,512

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis

2013 · Patrick M. Smith, Michael R. Howitt, et al. · Science · 5,392

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

2004 · Tyler J Curiel, George Coukos, et al. · Nature Medicine · 5,147

IL-17 and Th17 Cells

2009 · Thomas Korn, Estelle Bettelli, et al. · Annual Review of Immunology · 4,869

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

2013 · Nicholas Arpaia, Clarissa Campbell, et al. · Nature · 4,814

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

2003 · WanJun Chen, Wenwen Jin, et al. · The Journal of Experimental Medicine · 4,703

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The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

2017 · Lu Zhang, Jianghao Xu, et al. · Cellular Physiology and Biochemistry · 4,089

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

2010 · Koji Atarashi, Takeshi Tanoue, et al. · Science · 3,749

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 · Craig L. Bennett, Jacinda Christie, et al. · Nature Genetics · 3,404

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 · Roli Khattri, Tom Cox, et al. · Nature Immunology · 2,860

Regulatory T Cells: Mechanisms of Differentiation and Function

2007 · Steven Z. Josefowicz, Li-Fan Lu, et al. · Annual Review of Immunology · 2,858

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

2005 · Shimon Sakaguchi · Nature Immunology · 2,674

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

2001 · Mary E. Brunkow, Eric W. Jeffery, et al. · Nature Genetics · 2,638

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 · Weihong Liu, Amy L. Putnam, et al. · The Journal of Experimental Medicine · 2,604

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

2007 · Silvia Deaglio, Karen M. Dwyer, et al. · The Journal of Experimental Medicine · 2,472

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Intraepithelial CD8 + tumor-infiltrating lymphocytes and a high CD8 + /regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

2005 · Eiichi Sato, Sara H. Olson, et al. · Proceedings of the National Academy of Sciences · 2,374

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

2009 · Makoto Miyara, Yumiko Yoshioka, et al. · Immunity · 2,289

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Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 · Jason D. Fontenot, Jeffrey P. Rasmussen, et al. · Immunity · 2,280

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PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

2009 · Loise M. Francisco, Victor H. Salinas, et al. · The Journal of Experimental Medicine · 2,081

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

2007 · Lauren W. Collison, Creg J. Workman, et al. · Nature · 2,066

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

2001 · Robert S. Wildin, Fred Ramsdell, et al. · Nature Genetics · 1,922

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

2008 · Liang Zhou, Jared E. Lopes, et al. · Nature · 1,864

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Works count: 28,100

Citation count: 999,300