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Keyword

FTH1

Description: FTH1 is a human protein-coding gene that encodes the ferritin heavy chain, a component of cellular iron storage.
Wikidata ID: wiki/Q17930834
OpenAlex ID: keywords/fth1
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 · Xiaofang Sun, Zhanhui Ou, et al. · Hepatology · 2,004
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Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
2014 · William E. Dowdle, Beat Nyfeler, et al. · Nature Cell Biology · 754
Identification of the gene responsible for Best macular dystrophy
1998 · Konstantin Petrukhin, Markus J. Koisti, et al. · Nature Genetics · 689
Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species
2004 · Can G. Pham, Concetta Bubici, et al. · Cell · 662
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Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis
2015 · Joseph D Mancias, Laura Pontano Vaites, et al. · eLife · 549
Inhibiting Ferroptosis through Disrupting the NCOA4–FTH1 Interaction: A New Mechanism of Action
2021 · Yuying Fang, Xiucai Chen, et al. · ACS Central Science · 513
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer
2022 · Shumin Ouyang, Huaxuan Li, et al. · Redox Biology · 507
FTH1 Inhibits Ferroptosis Through Ferritinophagy in the 6-OHDA Model of Parkinson's Disease
2020 · Ye Tian, Juan Lu, et al. · Neurotherapeutics · 422
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Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy
2020 · Shuangwen Li, Lisi Zheng, et al. · Free Radical Biology and Medicine · 408
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis
2020 · Dominik C. Fuhrmann, Antonia Mondorf, et al. · Redox Biology · 405
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Iron‐regulated DNA binding by the AFT1 protein controls the iron regulon in yeast.
1996 · Y. Yamaguchi‐Iwai, R. Stearman, et al. · The EMBO Journal · 337
A Quantitative Analysis of Isoferritins in Select Regions of Aged, Parkinsonian, and Alzheimer's Diseased Brains
1995 · James R. Connor, Brian S. Snyder, et al. · Journal of Neurochemistry · 317
Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1
2021 · Na Kong, Xiaying Chen, et al. · Acta Pharmaceutica Sinica B · 298
The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene.
1988 · S V Torti, E L Kwak, et al. · Journal of Biological Chemistry · 296
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis
2022 · Fan Yu, Qianping Zhang, et al. · Cell Discovery · 274
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Controlling Assembly of Paired Gold Clusters within Apoferritin Nanoreactor for in Vivo Kidney Targeting and Biomedical Imaging
2011 · Cuiji Sun, Hui Yang, et al. · Journal of the American Chemical Society · 274
PM2.5 induces ferroptosis in human endothelial cells through iron overload and redox imbalance
2019 · Yan Wang, Meng Tang · Environmental Pollution · 253
Ferroptosis mediated DSS-induced ulcerative colitis associated with Nrf2/HO-1 signaling pathway
2020 · Yeru Chen, Piao Zhang, et al. · Immunology Letters · 242
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Biomimetic Design of Mitochondria‐Targeted Hybrid Nanozymes as Superoxide Scavengers
2021 · Yue Zhang, Anila Khalique, et al. · Advanced Materials · 233
Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury
2013 · Abolfazl Zarjou, Subhashini Bolisetty, et al. · Journal of Clinical Investigation · 209
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Role of ferritin alterations in human breast cancer cells
2010 · Svitlana I. Shpyleva, Volodymyr P. Tryndyak, et al. · Breast Cancer Research and Treatment · 206
Curcumenol triggered ferroptosis in lung cancer cells via lncRNA H19/miR-19b-3p/FTH1 axis
2021 · Ruonan Zhang, Ting Pan, et al. · Bioactive Materials · 205
Resveratrol protects against myocardial ischemia-reperfusion injury via attenuating ferroptosis
2021 · Ting Li, Ying Tan, et al. · Gene · 205
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YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis
2022 · Jing Zhang, Yongping Zheng, et al. · Frontiers in Immunology · 201
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines
2021 · Yulin Zhang, Yang Kong, et al. · Oncogene · 192
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Works count: 1,898
Citation count: 38,940
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