Keyword

FUS

Description: A human gene encoding an RNA-binding protein involved in RNA processing and associated with neurodegenerative disease research.

Primary topic: Amyotrophic Lateral Sclerosis Research (50%)

Wikidata ID: wiki/Q18024775

OpenAlex ID: keywords/fus

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

2009 · Caroline Vance, Boris Rogelj, et al. · Science · 2,565

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

2018 · Jie Wang, Jeong-Mo Choi, et al. · Cell · 2,084

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State of play in amyotrophic lateral sclerosis genetics

2013 · Alan E Renton, Adriano Chiò, et al. · Nature Neuroscience · 1,546

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Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

2011 · Magdalini Polymenidou, Clotilde Lagier-Tourenne, et al. · Nature Neuroscience · 1,332

Mutations of optineurin in amyotrophic lateral sclerosis

2010 · Hirofumi Maruyama, Hiroyuki Morino, et al. · Nature · 1,262

RNA buffers the phase separation behavior of prion-like RNA binding proteins

2018 · Shovamayee Maharana, Jie Wang, et al. · Science · 1,109

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

2010 · Ian RA Mackenzie, Rosa Rademakers, et al. · The Lancet Neurology · 976

Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets

2016 · Yongdae Shin, Joel Berry, et al. · Cell · 967

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Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

2015 · Kathleen A. Burke, Abigail M. Janke, et al. · Molecular Cell · 932

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Stress granules as crucibles of ALS pathogenesis

2013 · Yun R. Li, Oliver D. King, et al. · The Journal of Cell Biology · 923

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

2018 · Seema Qamar, GuoZhen Wang, et al. · Cell · 905

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ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

2015 · Tetsuro Murakami, Seema Qamar, et al. · Neuron · 868

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Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

2012 · Tina W. Han, Masato Kato, et al. · Cell · 768

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MicroRNA sequence codes for small extracellular vesicle release and cellular retention

2021 · Ruben Garcia-Martin, Guoxiao Wang, et al. · Nature · 734

Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity

2017 · Zachary Monahan, Veronica H Ryan, et al. · The EMBO Journal · 685

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Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

2018 · Mario Hofweber, Saskia Hutten, et al. · Cell · 670

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Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons

2014 · Brian J. Wainger, Evangelos Kiskinis, et al. · Cell Reports · 662

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The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

2012 · Oliver D. King, Aaron D. Gitler, et al. · Brain Research · 644

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

2010 · H. Seelaar, J. D. Rohrer, et al. · Journal of Neurology Neurosurgery & Psychiatry · 611

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Protein aggregation in amyotrophic lateral sclerosis

2013 · Anna M. Blokhuis, Ewout J. N. Groen, et al. · Acta Neuropathologica · 580

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Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

1993 · T.H. Rabbitts, A. Forster, et al. · Nature Genetics · 554

Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains

2013 · Ilmin Kwon, Masato Kato, et al. · Cell · 547

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FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

2017 · Lorenzo Errichelli, Stefano Dini Modigliani, et al. · Nature Communications · 541

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Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis

2017 · Zhang-Yu Zou, Zhi-Rui Zhou, et al. · Journal of Neurology Neurosurgery & Psychiatry · 538

The heritability and genetics of frontotemporal lobar degeneration

2009 · J. D. Rohrer, R. Guerreiro, et al. · Neurology · 536

Works count: 3,046

Citation count: 99,850