Get started
Keyword

gedunin

Description: A naturally occurring limonoid compound found in neem and other plants, investigated for biological activity including potential anticancer effects.
Wikidata ID: wiki/Q15917840
OpenAlex ID: keywords/gedunin
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
2006 · Haley Hieronymus, Justin Lamb, et al. · Cancer Cell · 625
PDF
Neem (Azadirachta indica): An indian traditional panacea with modern molecular basis
2017 · Subash Chandra Gupta, Sahdeo Prasad, et al. · Phytomedicine · 257
Effects of neem limonoids on the malaria vector Anopheles stephensi Liston (Diptera: Culicidae)
2005 · Sengottayan Senthil Nathan, Kandaswamy Kalaivani, et al. · Acta Tropica · 212
Antimalarial Activity of Tropical Meliaceae Extracts and Gedunin Derivatives
1997 · S. MacKinnon, T. Durst, et al. · Journal of Natural Products · 201
Isolation and characterization of an antimalarial agent of the neem tree Azadirachta indica
1989 · Sami A. Khalid, Helmut Duddeck, et al. · Journal of Natural Products · 176
Gedunin, a Novel Hsp90 Inhibitor: Semisynthesis of Derivatives and Preliminary Structure−Activity Relationships
2008 · Gary E. L. Brandt, Matthew D. Schmidt, et al. · Journal of Medicinal Chemistry · 166
Exploring the role of Azadirachta indica (neem) and its active compounds in the regulation of biological pathways: an update on molecular approach
2021 · Subendu Sarkar, Rajender Pal Singh, et al. · 3 Biotech · 152
Potential antimalarial candidates from African plants: An in vitro approach using Plasmodium falciparum
1986 · Sami A. Khalid, Asim Farouk, et al. · Journal of Ethnopharmacology · 150
Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis
2013 · Chaitanya A. Patwardhan, Abdul Fauq, et al. · Journal of Biological Chemistry · 148
PDF
In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae)
2000 · Jean Bickii, Njikam Njifutie, et al. · Journal of Ethnopharmacology · 146
Plants as sources of antimalarial drugs. Part 7. Activity of some species of meliaceae plants and their constituent limonoids
1990 · D. H. Bray, D. C. Warhurst, et al. · Phytotherapy Research · 146
Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo‐2 colon cancer cell line In Vitro
2007 · Shaikh J. Uddin, Lutfun Nahar, et al. · Phytotherapy Research · 124
The toxicity and physiological effect of neem limonoids on Cnaphalocrocis medinalis (Guenée) the rice leaffolder
2004 · S. Senthil Nathan, K. Kalaivani, et al. · Pesticide Biochemistry and Physiology · 120
Growth Inhibitory Effects on Fall Armyworm Spodoptera frugiperda of Some Limonoids Isolated from Cedrela spp. (Meliaceae)
2000 · Carlos L. Céspedes, José S. Calderón, et al. · Journal of Agricultural and Food Chemistry · 117
Cytotoxic and Apoptosis-Inducing Activities of Limonoids from the Seeds of Azadirachta indica (Neem)
2011 · Takashi Kikuchi, Koichi Ishii, et al. · Journal of Natural Products · 114
Constituents of Azadirachta indica: Isolation and Structure Elucidation of a New Antibacterial Tetranortriterpenoid, Mahmoodin, and a New Protolimonoid, Naheedin
1992 · Salimuzzaman Siddiqui, Shaheen Faizi, et al. · Journal of Natural Products · 102
Deoxygedunin, a Natural Product with Potent Neurotrophic Activity in Mice
2010 · Sung-Wuk Jang, Xia Liu, et al. · PLoS ONE · 101
PDF
The Limonoids and Their Antitobacco Mosaic Virus (TMV) Activities from Munronia unifoliolata Oliv.
2012 · Yong-hui Ge, Kai-xing Liu, et al. · Journal of Agricultural and Food Chemistry · 100
Gedunin and Photogedunin of Xylocarpus granatum show significant anti-secretory effects and protect the gastric mucosa of peptic ulcer in rats
2009 · V. Lakshmi, N. Singh, et al. · Phytomedicine · 100
Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators
2011 · Natalya A. Smirnova, Renee E. Haskew-Layton, et al. · Chemistry & Biology · 95
Antiplasmodial activity of the andiroba (Carapa guianensis Aubl., Meliaceae) oil and its limonoid-rich fraction
2012 · Raimundo Nonato Cardoso Miranda Júnior, Maria Fâni Dolabela, et al. · Journal of Ethnopharmacology · 92
PDF
Limonoids from andiroba oil and Cedrela fissilis and their insecticidal activity
2006 · Alessandra R. P. Ambrozin, Ana C. Leite, et al. · Journal of the Brazilian Chemical Society · 91
PDF
Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor
2010 · Vivek R. Yadav, Bokyung Sung, et al. · Journal of Molecular Medicine · 88
Antiplasmodial Triterpenoids from the Fruits of Neem, Azadirachta indica
2010 · Giuseppina Chianese, Serge R. Yerbanga, et al. · Journal of Natural Products · 88
Therapeutic Potential of Medicinal Plants and Their Phytoconstituents in Diabetes, Cancer, Infections, Cardiovascular Diseases, Inflammation and Gastrointestinal Disorders
2025 · Prawej Ansari, Alexa D. Reberio, et al. · Biomedicines · 87
PDF
Works count: 323
Citation count: 8,018
Year
Topic
Type