Keyword

glucuronidation

Description: Glucuronidation is a metabolic conjugation process in which glucuronic acid is attached to compounds, often increasing their water solubility and facilitating excretion.

Primary topic: Pharmacogenetics and Drug Metabolism (48%)

OpenAlex ID: keywords/glucuronidation

Polyphenols: food sources and bioavailability

2004 · Claudine Manach, Augustin Scalbert, et al. · American Journal of Clinical Nutrition · 8,167

Dietary phenolics: chemistry, bioavailability and effects on health

2009 · Alan Crozier, Indu B. Jaganath, et al. · Natural Product Reports · 1,990

Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease

2000 · Robert H. Tukey, Christian P. Strassburg · The Annual Review of Pharmacology and Toxicology · 1,524

Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin

2006 · Abdellah Zinedine, Jose Miguel Soriano, et al. · Food and Chemical Toxicology · 1,431

Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

2017 · Maud A. S. Weerink, Michel M. R. F. Struys, et al. · Clinical Pharmacokinetics · 1,209

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Bioavailability of resveratrol

2011 · Thomas Walle · Annals of the New York Academy of Sciences · 1,047

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Metabolism and Kinetics of Bisphenol A in Humans at Low Doses Following Oral Administration

2002 · Wolfgang Völkel, Thomas Colnot, et al. · Chemical Research in Toxicology · 1,006

Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potential

1996 · J.R.S. Hoult, Miguel Payá · General Pharmacology The Vascular System · 951

Biotransformation of Curcumin Through Reduction and Glucuronidation in Mice

1999 · Min-Hsiung Pan, Tsang-Miao Huang, et al. · Drug Metabolism and Disposition · 949

Drug-drug Interactions for Udp-glucuronosyltransferase Substrates: a Pharmacokinetic Explanation for Typically Observed Low Exposure (auci/auc) Ratios

2004 · J. Andrew Williams, Ruth Hyland, et al. · Drug Metabolism and Disposition · 929

Bioactivity of phenolic acids: Metabolites versus parent compounds: A review

2014 · Sandrina A. Heleno, Anabela Martins, et al. · Food Chemistry · 901

Clinical Pharmacokinetics of Mycophenolate Mofetil

1998 · Roy E.S. Bullingham, Andrew J. Nicholls, et al. · Clinical Pharmacokinetics · 839

Phase I Dose Escalation Pharmacokinetic Study in Healthy Volunteers of Resveratrol, a Potential Cancer Chemopreventive Agent

2007 · David J. Boocock, Guy E.S. Faust, et al. · Cancer Epidemiology Biomarkers & Prevention · 824

Glucuronidation of Drugs and Other Compounds

2019 · Geoffrey J. Dutton · Chapman & Hall/CRC eBooks · 794

The biological activities, chemical stability, metabolism and delivery systems of quercetin: A review

2016 · Weiyou Wang, Cuixia Sun, et al. · Trends in Food Science & Technology · 784

Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics

2016 · Xiaoxv Dong, Jing Fu, et al. · Phytotherapy Research · 763

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Clinical pharmacokinetics and metabolism of irinotecan (CPT-11).

2001 · R H Mathijssen, R J van Alphen, et al. · PubMed · 744

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RETRACTED: Quercetin: A flavonol with multifaceted therapeutic applications?

2015 · Gabriele D'Andrea · Fitoterapia · 722

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

2002 · L Iyer, S Das, et al. · The Pharmacogenomics Journal · 720

Flavonoid Antioxidants

2001 · Catherine Rice-Evans · Current Medicinal Chemistry · 719

Absorption and metabolism of polyphenols in the gut and impact on health

2002 · Augustin Scalbert, Christine Morand, et al. · Biomedicine & Pharmacotherapy · 717

Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability.

2002 · Mao-Jung Lee, Pius Maliakal, et al. · PubMed · 716

The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification

2013 · Andrew Rowland, John O. Miners, et al. · The International Journal of Biochemistry & Cell Biology · 710

Metabolism and Disposition of Acetaminophen: Recent Advances in Relation to Hepatotoxicity and Diagnosis

2013 · Mitchell R. McGill, Hartmut Jaeschke · Pharmaceutical Research · 704

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

1998 · L Iyer, C D King, et al. · Journal of Clinical Investigation · 686

Works count: 13,100

Citation count: 382,200