Keyword

gp120

Description: gp120 is a glycoprotein on the HIV envelope that binds host-cell receptors during viral attachment and entry.

Primary topic: HIV Research and Treatment (75%)

Related topic: HIV Research and Treatment (75%)

Wikidata ID: wiki/Q182506

OpenAlex ID: keywords/gp120

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1998 · Peter D. Kwong, Richard Wyatt, et al. · Nature · 2,964

DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells

2000 · Teunis B.H Geijtenbeek, Douglas S Kwon, et al. · Cell · 2,446

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Core Structure of gp41 from the HIV Envelope Glycoprotein

1997 · David C. Chan, Deborah Fass, et al. · Cell · 1,959

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Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

2010 · Xueling Wu, Zhi-Yong Yang, et al. · Science · 1,732

Broad neutralization coverage of HIV by multiple highly potent antibodies

2011 · Laura M. Walker, Michael Huber, et al. · Nature · 1,480

Genotypic and Phenotypic Characterization of HIV-1 Patients with Primary Infection

1993 · Tuofu Zhu, Hongmei Mo, et al. · Science · 1,249

The antigenic structure of the HIV gp120 envelope glycoprotein

1998 · Richard Wyatt, Peter D. Kwong, et al. · Nature · 1,203

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The Immunopathogenesis of Human Immunodeficiency Virus Infection

1993 · Franklin H. Epstein, Giuseppe Pantaleo, et al. · New England Journal of Medicine · 1,190

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5

1996 · Lijun Wu, Norma P. Gerard, et al. · Nature · 1,168

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

2010 · Tongqing Zhou, Ivelin Georgiev, et al. · Science · 1,132

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

1996 · A Trkola, M Purtscher, et al. · Journal of Virology · 1,115

Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody

1994 · Dennis R. Burton, Jayashree Pyati, et al. · Science · 1,100

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

1996 · Alexandra Trkola, Tatjana Dragic, et al. · Nature · 1,034

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

2013 · Hua-Xin Liao, Rebecca Lynch, et al. · Nature · 989

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

1990 · C K Leonard, M W Spellman, et al. · Journal of Biological Chemistry · 986

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 · Michael O. Westendorp, Rainer Frank, et al. · Nature · 976

Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design

2001 · Erica Ollmann Saphire, Paul W. H. I. Parren, et al. · Science · 941

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 · Laurence A. Lasky, Gerald Nakamura, et al. · Cell · 828

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

1993 · Dennis W. Dickson, Sunhee C. Lee, et al. · Glia · 825

Molecular architecture of native HIV-1 gp120 trimers

2008 · Jun Liu, Alberto Bartesaghi, et al. · Nature · 815

Distribution and three-dimensional structure of AIDS virus envelope spikes

2006 · Ping Zhu, Jun Liu, et al. · Nature · 779

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

1992 · R A Fouchier, M Groenink, et al. · Journal of Virology · 771

Structural definition of a conserved neutralization epitope on HIV-1 gp120

2007 · Tongqing Zhou, Ling Xu, et al. · Nature · 770

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In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity

1988 · R L Willey, D H Smith, et al. · Journal of Virology · 751

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

2014 · Marie Pancera, Tongqing Zhou, et al. · Nature · 743

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Works count: 6,530

Citation count: 256,500