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Keyword

gp130

Description: A transmembrane signal-transducing protein that serves as a shared receptor component for the interleukin-6 family of cytokines.
OpenAlex ID: keywords/gp130
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 · Peter C. HEINRICH, Iris BEHRMANN, et al. · Biochemical Journal · 3,272
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The pro- and anti-inflammatory properties of the cytokine interleukin-6
2011 · Jürgen Scheller, Athena Chalaris, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 3,214
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
1998 · Peter C. HEINRICH, Iris BEHRMANN, et al. · Biochemical Journal · 2,128
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Impaired immune and acute-phase responses in interleukin-6-deficient mice
1994 · Manfred Kopf, Heinz Baumann, et al. · Nature · 1,767
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
1998 · Hitoshi Niwa, Tom Burdon, et al. · Genes & Development · 1,549
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gp 130 AND THE INTERLEUKIN-6 FAMILY OF CYTOKINES
1997 · Tetsuya Taga, Tadamitsu Kishimoto · Annual Review of Immunology · 1,461
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
1989 · Tetsuya Taga, Masahiko Hibi, et al. · Cell · 1,396
Molecular cloning and expression of an IL-6 signal transducer, gp130
1990 · Masahiko Hibi, Masaaki Murakami, et al. · Cell · 1,305
Structure and function of a new STAT-induced STAT inhibitor
1997 · Tetsuji Naka, Masashi Narazaki, et al. · Nature · 1,288
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Interleukin-6 family of cytokines and gp130
1995 · T Kishimoto, S Akira, et al. · Blood · 1,272
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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
2010 · Eli A Stahl, Soumya Raychaudhuri, et al. · Nature Genetics · 1,253
Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
2000 · Toshio Hirano, Katsuhiko Ishihara, et al. · Oncogene · 1,190
Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment
1997 · Maria Romano, Marina Sironi, et al. · Immunity · 1,112
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IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6
2012 · Stefan Rose-John · International Journal of Biological Sciences · 1,035
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INTERLEUKIN-6: From Basic Science to Medicine—40 Years in Immunology
2004 · Tadamitsu Kishimoto · Annual Review of Immunology · 1,024
Association and Activation of Jak-Tyk Kinases by CNTF-LIF-OSM-IL-6 β Receptor Components
1994 · Neil Stahl, Teri G. Boulton, et al. · Science · 980
Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors
1995 · Neil Stahl, Thomas J. Farruggella, et al. · Science · 979
Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major
2018 · Shanshan Hu, Cameron Marshall, et al. · Frontiers in Immunology · 973
gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
2009 · Julia Bollrath, Toby J. Phesse, et al. · Cancer Cell · 945
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β1-6 Branching of Asn-Linked Oligosaccharides Is Directly Associated with Metastasis
1987 · James W. Dennis, Suzanne Laferté, et al. · Science · 939
IL-6/IL-6 receptor system and its role in physiological and pathological conditions
2011 · Masahiko Mihara, Misato Hashizume, et al. · Clinical Science · 895
STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
1999 · Takahiko Matsuda, Takanori Nakamura, et al. · The EMBO Journal · 895
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The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor
1992 · David P. Gearing, Michael R. Comeau, et al. · Science · 889
IL-6 pathway in the liver: From physiopathology to therapy
2016 · Dirk Schmidt-Arras, Stefan Rose-John · Journal of Hepatology · 881
Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses
1998 · Scott J Rodig, Marco A Meraz, et al. · Cell · 854
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Works count: 4,546
Citation count: 213,600
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