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gp41
Description:
A transmembrane subunit of the HIV envelope glycoprotein complex involved in viral entry and targeted by neutralizing antibodies.
Primary topic:
HIV Research and Treatment (75%)
Related topics:
HIV Research and Treatment (75%),
HIV/AIDS drug development and treatment (7%)
OpenAlex ID:
keywords/gp41
Core Structure of gp41 from the HIV Envelope Glycoprotein
1997
·
David C. Chan
, Deborah Fass
, et al.
·
Cell
·
1,959
PDF
Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy
2002
·
Xiping Wei
, Julie M. Decker
, et al.
·
Antimicrobial Agents and Chemotherapy
·
1,565
Genotypic and Phenotypic Characterization of HIV-1 Patients with Primary Infection
1993
·
Tuofu Zhu
, Hongmei Mo
, et al.
·
Science
·
1,249
The Immunopathogenesis of Human Immunodeficiency Virus Infection
1993
·
Franklin H. Epstein
, Giuseppe Pantaleo
, et al.
·
New England Journal of Medicine
·
1,190
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
1993
·
T Muster
, F Steindl
, et al.
·
Journal of Virology
·
1,006
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
1998
·
J. Michael Kilby
, Sam Hopkins
, et al.
·
Nature Medicine
·
987
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.
1994
·
C T Wild
, D C Shugars
, et al.
·
Proceedings of the National Academy of Sciences
·
931
PDF
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
2012
·
Jinghe Huang
, Gilad Ofek
, et al.
·
Nature
·
831
Human immunodeficiency virus reverse transcriptase and protease sequence database
2003
·
S.-Y. Rhee
·
Nucleic Acids Research
·
817
PDF
Molecular architecture of native HIV-1 gp120 trimers
2008
·
Jun Liu
, Alberto Bartesaghi
, et al.
·
Nature
·
815
Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41
2001
·
Michael B. Zwick
, Aran F. Labrijn
, et al.
·
Journal of Virology
·
797
Evidence for Budding of Human Immunodeficiency Virus Type 1 Selectively from Glycolipid-Enriched Membrane Lipid Rafts
2000
·
Dzung H. Nguyen
, James E. K. Hildreth
·
Journal of Virology
·
789
Cardiolipin Polyspecific Autoreactivity in Two Broadly Neutralizing HIV-1 Antibodies
2005
·
Barton F. Haynes
, Judith Fleming
, et al.
·
Science
·
745
Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies
2004
·
James M. Binley
, Terri Wrin
, et al.
·
Journal of Virology
·
705
A trimeric structural domain of the HIV-1 transmembrane glycoprotein
1995
·
Min Lu
, Stephen C. Blacklow
, et al.
·
Nature Structural & Molecular Biology
·
702
Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
1995
·
Jonathan D. Glass
, Helen Fedor
, et al.
·
Annals of Neurology
·
662
Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding.
1991
·
Q J Sattentau
, J P Moore
·
The Journal of Experimental Medicine
·
601
Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4
1990
·
John P. Moore
, Jane A. McKeating
, et al.
·
Science
·
577
Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion
2000
·
Grigory B. Melikyan
, Ruben M. Markosyan
, et al.
·
The Journal of Cell Biology
·
576
A Recombinant Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Complex Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits Is an Antigenic Mimic of the Trimeric Virion-Associated Structure
2000
·
James M. Binley
, Rogier W. Sanders
, et al.
·
Journal of Virology
·
534
Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection
2008
·
D. Noah Sather
, Jakob Armann
, et al.
·
Journal of Virology
·
528
A Potent Cross-Clade Neutralizing Human Monoclonal Antibody against a Novel Epitope on gp41 of Human Immunodeficiency Virus Type 1
2001
·
Gabriela Stiegler
, Renate Kunert
, et al.
·
AIDS Research and Human Retroviruses
·
518
Capture of an early fusion-active conformation of HIV-1 gp41
1998
·
Rika A. Furuta
, Carl T. Wild
, et al.
·
Nature Structural Biology
·
488
HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation
2011
·
Mary Ann Checkley
, Benjamin G. Luttge
, et al.
·
Journal of Molecular Biology
·
479
Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41
2005
·
Rosa M.F. Cardoso
, Michael B. Zwick
, et al.
·
Immunity
·
450
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Works count:
3,083
Citation count:
110,700
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