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Keyword

GPR14

Description: A gene encoding the urotensin II receptor, a G protein-coupled receptor studied in cardiovascular, neural, and other biological contexts.
Wikidata ID: wiki/Q15319948
OpenAlex ID: keywords/gpr14
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
1999 · Robert S. Ames, Henry M. Sarau, et al. · Nature · 791
Congestive heart failure and expression of myocardial urotensin II
2002 · Stephen A Douglas, Lara Tayara, et al. · The Lancet · 262
Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues
2001 · Mika Matsushita, Masayoshi Shichiri, et al. · Journal of Hypertension · 244
Identification of Urotensin II as the Endogenous Ligand for the Orphan G-Protein-Coupled Receptor GPR14
1999 · Qingyun Liu, Sheng-Shung Pong, et al. · Biochemical and Biophysical Research Communications · 244
Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey
2000 · Stephen A Douglas, Anthony C Sulpizio, et al. · British Journal of Pharmacology · 228
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Urotensin II Is the Endogenous Ligand of a G-Protein-Coupled Orphan Receptor, SENR (GPR14)
1999 · Masaaki Mori, Tsukasa Sugo, et al. · Biochemical and Biophysical Research Communications · 207
Human Urotensin-II, the Most Potent Mammalian Vasoconstrictor Identified To Date, as a Therapeutic Target for the Management of Cardiovascular Disease
2000 · Stephen A. Douglas, Eliot H. Ohlstein · Trends in Cardiovascular Medicine · 194
Cloning and Chromosomal Mapping of Three Novel Genes, GPR9, GPR10, and GPR14, Encoding Receptors Related to Interleukin 8, Neuropeptide Y, and Somatostatin Receptors
1995 · ADRIANO MARCHESE, MICHAEL HEIBER, et al. · Genomics · 192
Identification of Nonpeptidic Urotensin II Receptor Antagonists by Virtual Screening Based on a Pharmacophore Model Derived from Structure−Activity Relationships and Nuclear Magnetic Resonance Studies on Urotensin II
2002 · Stefanie Flohr, Michael Kurz, et al. · Journal of Medicinal Chemistry · 178
Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain
2003 · Tsukasa Sugo, Yuko Murakami, et al. · Biochemical and Biophysical Research Communications · 173
Plasma Urotensin in Human Systolic Heart Failure
2002 · Leong L. Ng, Ian Loke, et al. · Circulation · 155
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Role of urotensin II in health and disease
2010 · Bryan Ross, Katherine McKendy, et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 144
Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta
2004 · Nicolas Bousette, Lisa Patel, et al. · Atherosclerosis · 129
Structure–activity relationships and structural conformation of a novel urotensin II-related peptide
2004 · David Chatenet, Christophe Dubessy, et al. · Peptides · 103
Central effects of urotensin-II following ICV administration in rats
2001 · Jane Gartlon, Frederick Parker, et al. · Psychopharmacology · 77
Elevated plasma human urotensin-II-like immunoreactivity in ischemic cardiomyopathy
2003 · Harald Lapp, Guido Boerrigter, et al. · International Journal of Cardiology · 76
Urotensin II: the old kid in town
2004 · Döne Onan, Ross D. Hannan, et al. · Trends in Endocrinology and Metabolism · 73
Localization of the urotensin II receptor in the rat central nervous system
2006 · Sylvie Jégou, Dorthe Cartier, et al. · The Journal of Comparative Neurology · 69
Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)
2002 · Glenn E. Croston, Roger Olsson, et al. · Journal of Medicinal Chemistry · 67
Inhibition of Insulin Release by Urotensin II - A Study on the Perfused Rat Pancreas
2001 · R. A. Silvestre, J. Rodríguez-Gallardo, et al. · Hormone and Metabolic Research · 66
Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system
2002 · S D Katugampola, J J Maguire, et al. · Canadian Journal of Physiology and Pharmacology · 63
Urotensin Ii Mediates Erk1/2 Phosphorylation and Proliferation in Gpr14-transfected Cell Lines
2002 · Patrick Ziltener, Célia Mueller, et al. · Journal of Receptors and Signal Transduction · 58
Structure–activity relationships of urotensin II and URP
2007 · Jérôme Leprince, David Chatenet, et al. · Peptides · 51
Urotensin-II is present in pancreatic extracts and inhibits insulin release in the perfused rat pancreas
2004 · RA Silvestre, EM Egido, et al. · European Journal of Endocrinology · 51
Renal and vascular actions of urotensin II
2006 · N. Ashton · Kidney International · 50
Works count: 150
Citation count: 5,137
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