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Keyword

group sequential designs

Description: Study designs that specify interim analyses at successive stages, allowing trials to stop early while controlling statistical error rates.
OpenAlex ID: keywords/group-sequential-designs
Group Sequential Methods in the Design and Analysis of Clinical Trials
1977 · S. J. POCOCK · Biometrika · 1,830
Adaptive Designs for Clinical Trials
2016 · Deepak L. Bhatt, Cyrus Mehta · New England Journal of Medicine · 499
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Adaptive increase in sample size when interim results are promising: A practical guide with examples
2010 · Cyrus R. Mehta, Stuart J. Pocock · Statistics in Medicine · 366
Sample Size Calculations in Clinical Research
2008 · Ian White · Journal of the Royal Statistical Society Series A (Statistics in Society) · 299
Design and Analysis of Clinical Trials: Concepts and Methodologies
2013 · Shein‐Chung Chow, Jen‐pei Liu · 268
Interim Analyses for Randomized Clinical Trials: The Group Sequential Approach
1982 · Stuart J. Pocock · Biometrics · 264
A 6-Week Randomized, Placebo-Controlled Trial of CP-316,311 (a Selective CRH 1 Antagonist) in the Treatment of Major Depression
2008 · Brendon Binneman, Douglas Feltner, et al. · American Journal of Psychiatry · 253
Group sequential designs using a family of type I error probability spending functions
1990 · Irving K. Hwang, Weichung J. Shih, et al. · Statistics in Medicine · 248
Parameter Estimation Following Group Sequential Hypothesis Testing
1990 · SCOTT S. EMERSON, THOMAS R. FLEMING · Biometrika · 224
Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis
1994 · Sandro Pampallona, Anastasios A. Tsiatis · Journal of Statistical Planning and Inference · 219
Handbook of Survival Analysis
2016 · Lange, Theis, Rod, Naja Hulvej · Chapman & Hall/CRC eBooks · 206
Adaptive design clinical trials: a review of the literature and ClinicalTrials.gov
2018 · Laura E Bothwell, Jerry Avorn, et al. · BMJ Open · 196
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Practical Nonparametric and Semiparametric Bayesian Statistics
1999 · Eric R. Ziegel, D. D. Dey, et al. · Technometrics · 192
Group Sequential Clinical Trials with Triangular Continuation Regions
1983 · John Whitehead, Irene Stratton · Biometrics · 189
Mid‐course sample size modification in clinical trials based on the observed treatment effect
2003 · Christopher Jennison, Bruce W. Turnbull · Statistics in Medicine · 180
Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
2016 · Gernot Wassmer, Werner Brannath · Springer series in pharmaceutical statistics · 178
Semiparametric Efficiency and Its Implication on the Design and Analysis of Group-Sequential Studies
1997 · Daniel O. Scharfstein, Anastasios A. Tsiatis, et al. · Journal of the American Statistical Association · 170
Statistical issues and challenges in immuno-oncology
2013 · Tai-Tsang Chen · Journal for ImmunoTherapy of Cancer · 168
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Practical problems in interim analyses, with particular regard to estimation
1989 · Stuart J. Pocock, Michael D. Hughes · Controlled Clinical Trials · 160
Monitoring of clinical trials: Issues and recommendations
1993 · Thomas R. Fleming, David L. DeMets · Controlled Clinical Trials · 141
Symmetric Group Sequential Test Designs
1989 · Scott S. Emerson, Thomas R. Fleming · Biometrics · 140
Predictive Probability Early Termination Plans For Phase II Clinical Trials
1979 · Jay Herson · Biometrics · 139
Designs for Group Sequential Phase II Clinical Trials
1987 · Myron N. Chang, Terry M. Therneau, et al. · Biometrics · 135
Seamlessly Expanding a Randomized Phase II Trial to Phase III
2002 · Lurdes Y. T. Inoue, Peter F. Thall, et al. · Biometrics · 133
Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial
2020 · and the Saudi Critical Care Trials group, Yaseen M. Arabi, et al. · Trials · 128
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Works count: 973
Citation count: 15,630
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