Keyword

GST polymorphisms

Description: Genetic variations in glutathione S-transferase genes that can influence enzyme function and are investigated in relation to disease and exposures.

Primary topic: Glutathione Transferases and Polymorphisms (69%)

OpenAlex ID: keywords/gst-polymorphisms

The role of glutathione-S-transferase in anti-cancer drug resistance

2003 · Danyelle M Townsend, Kenneth D Tew · Oncogene · 1,352

Glutathione S-Transferase Polymorphisms and Their Biological Consequences

2000 · John D. Hayes, Richard C. Strange · Pharmacology · 1,001

Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases

2018 · Nerino Allocati, Michele Masulli, et al. · Oncogenesis · 624

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Glutathione S-transferase: genetics and role in toxicology

2000 · Richard C Strange, Peter W Jones, et al. · Toxicology Letters · 376

Human Glutathione S-Transferases

1998 · Richard Whalen, Thomas Boyer · Seminars in Liver Disease · 350

The glutathione S-transferases: influence of polymorphism on cancer susceptibility.

1999 · R C Strange, A A Fryer · PubMed · 302

Detoxification of electrophilic compounds by glutathione S‐transferase catalysis: Determinants of individual response to chemical carcinogens and chemotherapeutic drugs?

2003 · Brian F. Coles, Fred F. Kadlubar · BioFactors · 219

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Combined effect of polymorphic GST genes on individual susceptibility to lung cancer

1998 · Sirkku T. Saarikoski, Anu Voho, et al. · International Journal of Cancer · 207

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The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma.

1993 · V Nazar-Stewart, A G Motulsky, et al. · PubMed · 176

Genetic Variations in Human Glutathione Transferase Enzymes: Significance for Pharmacology and Toxicology

2010 · P. David Josephy · Human Genomics and Proteomics · 159

Immunohistochemical localization of glutathione S-transferases in human lung.

1993 · S Anttila, A Hirvonen, et al. · PubMed · 158

Isothiocyanates: mechanism of cancer chemopreventive action

2002 · Paul J Thornalley · Anti-Cancer Drugs · 151

Pharmacokinetics and toxicity of docetaxel: Role of CYP3A, MDR1, and GST polymorphisms

2006 · A TRAN, V JULLIEN, et al. · Clinical Pharmacology & Therapeutics · 139

Divergent Activities of Human Glutathione Transferases in the Bioactivation of Azathioprine

2006 · Birgitta I. Eklund, My Moberg, et al. · Molecular Pharmacology · 129

Glutathione S-transferases in kidney and urinary bladder tumors

2009 · Tatjana Simic, Ana Savic-Radojevic, et al. · Nature Reviews Urology · 112

Rapid spectrophotometric method for serum glutathione S-transferases activity

2002 · Mohammed Habdous, Monique Vincent-Viry, et al. · Clinica Chimica Acta · 112

Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma.

1996 · C J Chen, M W Yu, et al. · PubMed · 109

Glutathione S-transferase M1 and T1 polymorphisms may predict adverse effects after therapy in children with medulloblastoma

2008 · Nadia Barahmani, Sarah Carpentieri, et al. · Neuro-Oncology · 86

Glutathione S‐transferase T1 null‐genotype is associated with an increased risk of lung cancer

2004 · Mette Sørensen, Herman Autrup, et al. · International Journal of Cancer · 85

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Liver glutathione S-transferase polymorphism in Japanese and its pharmacogenetic importance

1987 · Shoji Harada, Masato Abei, et al. · Human Genetics · 85

Glutathione S-transferase polymorphisms: influence on susceptibility to cancer

1998 · Richard C Strange, John T Lear, et al. · Chemico-Biological Interactions · 82

Heterogeneous expression and polymorphic genotype of glutathione S-transferases in human lung.

1994 · A M Cantlay, C A Smith, et al. · Thorax · 82

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Increased risk for acute myeloid leukaemia in individuals with glutathione S‐transferase mu 1 (GSTM1) and theta 1 (GSTT1) gene defects

2001 · Valder Roberval Arruda, Carmen Silvia Passos Lima, et al. · European Journal Of Haematology · 77

Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs

2010 · M. Villarini, L. Dominici, et al. · Mutagenesis · 75

Self-reported skin color, genomic ancestry and the distribution of GST polymorphisms

2007 · Guilherme Suarez-Kurtz, Daniela D. Vargens, et al. · Pharmacogenetics and Genomics · 75

Works count: 478

Citation count: 9,383