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Keyword

GSTA1

Description: GSTA1 is a human protein-coding gene that encodes glutathione S-transferase alpha 1, an enzyme involved in cellular detoxification.
Wikidata ID: wiki/Q18015279
OpenAlex ID: keywords/gsta1
Nomenclature for human glutathione transferases
1992 · B Mannervik, Y C Awasthi, et al. · Biochemical Journal · 671
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
2002 · Simon A. CHANAS, Qing JIANG, et al. · Biochemical Journal · 460
Hypermethylation of the Human Glutathione S-Transferase-π Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate
2003 · Masashi Nakayama, Christina J. Bennett, et al. · American Journal Of Pathology · 298
A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway
2002 · Yasujiro Morimitsu, Yoko Nakagawa, et al. · Journal of Biological Chemistry · 273
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Prediction of Recurrence-Free Survival in Postoperative Non–Small Cell Lung Cancer Patients by Using an Integrated Model of Clinical Information and Gene Expression
2008 · Eung-Sirk Lee, Dae-Soon Son, et al. · Clinical Cancer Research · 265
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Differential Induction of Distinct Glutathione-S-Transferases of Wheat by Xenobiotics and by Pathogen Attack
1993 · F. Mauch, R. Dudler · PLANT PHYSIOLOGY · 264
Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera
1997 · Jonathan D. ROWE, Edward NIEVES, et al. · Biochemical Journal · 229
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The Role of Aryl Hydrocarbon Receptor in the Pathogenesis of Cardiovascular Diseases
2006 · Hesham M. Korashy, Ayman O. S. El-Kadi · Drug Metabolism Reviews · 173
Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells
2002 · Graham P. Basten, Yongping Bao, et al. · Carcinogenesis · 150
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A Pathogen-Induced Wheat Gene Encodes a Protein Homologous to Glutathione-S-Transferases
1991 · Robert Dudler · Molecular Plant-Microbe Interactions · 147
Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk
2002 · Susan Nowell, Brian Coles, et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 146
Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide
2008 · Corine Ekhart, Valerie D. Doodeman, et al. · Pharmacogenetics and Genomics · 135
Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein
2007 · Larry G. Higgins, Christophe Cavin, et al. · Toxicology and Applied Pharmacology · 129
The human glutathione transferase alpha locus: genomic organization of the gene cluster and functional characterization of the genetic polymorphism in the hGSTA1 promoter.
2002 · Fabrice Morel, Claudine Rauch, et al. · Pharmacogenetics · 125
Synthesis and Characterization of a Series of Highly Fluorogenic Substrates for Glutathione Transferases, a General Strategy
2011 · Jie Zhang, Aya Shibata, et al. · Journal of the American Chemical Society · 121
Glutathione S-transferases and thiol concentrations in embryonic and early fetal tissues
2001 · M.T.M. Raijmakers, E.A.P. Steegers, et al. · Human Reproduction · 121
GSTA1 expression in normal, preneoplastic, and neoplastic human prostate tissue
2001 · J. Kellogg Parsons, Chad P. Nelson, et al. · The Prostate · 108
Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression
2020 · Kavitha Mukund, Natalia Syulyukina, et al. · BMC Cancer · 107
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Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19
2005 · R Timm, R Kaiser, et al. · The Pharmacogenomics Journal · 103
Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk
2004 · E.M.J. van der Logt · Carcinogenesis · 103
Effects of lead on rat kidney and liver: GST expression and oxidative stress
1998 · Daniel A Daggett, Terry D Oberley, et al. · Toxicology · 100
Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis
2016 · Da Hyun Lee, Dai Hoon Han, et al. · Free Radical Biology and Medicine · 97
Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells
2004 · V. Svehlikova · Carcinogenesis · 95
An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment
2008 · Corine Ekhart, Sjoerd Rodenhuis, et al. · Cancer Treatment Reviews · 94
Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility.
2006 · Edyta Reszka, Wojciech Wasowicz, et al. · PubMed · 93
Works count: 552
Citation count: 11,540
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