Keyword

HDAC2

Description: HDAC2 is a human gene encoding histone deacetylase 2, an enzyme involved in chromatin regulation and gene expression.

Primary topic: Histone Deacetylase Inhibitors Research (28%)

Wikidata ID: wiki/Q18026859

OpenAlex ID: keywords/hdac2

Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor

2012 · Tadahiro Shimazu, Matthew D. Hirschey, et al. · Science · 1,772

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Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

2016 · Peter J. Barnes · Journal of Allergy and Clinical Immunology · 1,690

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HDAC2 negatively regulates memory formation and synaptic plasticity

2009 · Ji-Song Guan, Stephen J. Haggarty, et al. · Nature · 1,638

Inhibition of Histone Deacetylase Activity by Butyrate

2003 · James R. Davie · Journal of Nutrition · 1,509

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

2011 · Frederick Anokye-Danso, Chinmay M. Trivedi, et al. · Cell stem cell · 1,210

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

1999 · Y. Zhang, H.-H. Ng, et al. · Genes & Development · 1,103

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

2000 · Michael R. Rountree, Kurtis E. Bachman, et al. · Nature Genetics · 1,054

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

2009 · Nitai C. Hait, Jeremy Allegood, et al. · Science · 998

Glucocorticoid resistance in inflammatory diseases

2009 · Peter J Barnes, Ian M Adcock · The Lancet · 984

Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease

2005 · Kazuhiro Ito, Misako Ito, et al. · New England Journal of Medicine · 970

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Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 · Carol D Laherty, Wen-Ming Yang, et al. · Cell · 939

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An epigenetic blockade of cognitive functions in the neurodegenerating brain

2012 · Johannes Gräff, Damien Rei, et al. · Nature · 850

How corticosteroids control inflammation: Quintiles Prize Lecture 2005

2006 · Peter J Barnes · British Journal of Pharmacology · 842

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Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

2022 · Carlos Moreno-Yruela, Di Zhang, et al. · Science Advances · 827

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

2016 · Sama F Sleiman, Jeffrey Henry, et al. · eLife · 809

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

2015 · Qian Zhang, Kai Zhao, et al. · Nature · 802

CpG methylation, chromatin structure and gene silencing—a three‐way connection

1998 · Aharon Razin · The EMBO Journal · 794

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Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex

2003 · Hector Peinado, Esteban Ballestar, et al. · Molecular and Cellular Biology · 764

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 · Christina M. Grozinger, Christian A. Hassig, et al. · Proceedings of the National Academy of Sciences · 764

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

2002 · Gerda Lagger, Dónal O'Carroll, et al. · The EMBO Journal · 760

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FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

2002 · Ryohei Furumai, Akihisa Matsuyama, et al. · PubMed · 732

The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression

2001 · Brian P. Ashburner, Sandy D. Westerheide, et al. · Molecular and Cellular Biology · 730

Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12

2000 · Kazuhiro Ito, Peter J. Barnes, et al. · Molecular and Cellular Biology · 723

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

2007 · Rusty L. Montgomery, Christopher A. Davis, et al. · Genes & Development · 714

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Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

2013 · Peter J. Barnes · Journal of Allergy and Clinical Immunology · 697

Works count: 4,540

Citation count: 155,700