Keyword

HDAC3

Description: A histone deacetylase encoded by the HDAC3 gene, involved in regulating gene expression and studied in cancer and other biological processes.

Primary topic: Histone Deacetylase Inhibitors Research (28%)

Wikidata ID: wiki/Q18033475

OpenAlex ID: keywords/hdac3

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

2005 · Gabriel Pascual, Amy L. Fong, et al. · Nature · 1,255

Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

2001 · Lin-feng Chen, Wolfgang Fischle, et al. · Science · 1,229

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The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

2015 · Colleen A. McHugh, Chun-Kan Chen, et al. · Nature · 1,159

Mechanisms of Tamoxifen Resistance: Increased Estrogen Receptor-HER2/neu Cross-Talk in ER/HER2-Positive Breast Cancer

2004 · J. Shou, S. Massarweh, et al. · JNCI Journal of the National Cancer Institute · 1,153

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

2011 · Weiwei Yang, Yan Xia, et al. · Nature · 1,028

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

1998 · Victoria M. Richon, Stephane Emiliani, et al. · Proceedings of the National Academy of Sciences · 909

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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

2012 · Weiwei Yang, Yan Xia, et al. · Cell · 846

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Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

2022 · Carlos Moreno-Yruela, Di Zhang, et al. · Science Advances · 825

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

2016 · Sama F Sleiman, Jeffrey Henry, et al. · eLife · 809

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 · Christina M. Grozinger, Christian A. Hassig, et al. · Proceedings of the National Academy of Sciences · 764

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

2002 · Gerda Lagger, Dónal O'Carroll, et al. · The EMBO Journal · 760

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Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR

2002 · Wolfgang Fischle, Franck Dequiedt, et al. · Molecular Cell · 753

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A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

2011 · Dan Feng, Tao Liu, et al. · Science · 697

NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

2008 · Guang-Hui Liu, Jing Qu, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 694

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Class II histone deacetylases: versatile regulators

2003 · Eric Verdin, Franck Dequiedt, et al. · Trends in Genetics · 662

Both corepressor proteins SMRT and N‐CoR exist in large protein complexes containing HDAC3

2000 · Jiwen Li, Jin Wang, et al. · The EMBO Journal · 629

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The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

2001 · Matthew G. Guenther, Orr Barak, et al. · Molecular and Cellular Biology · 611

NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance

2024 · Hengxing Chen, Yun Li, et al. · Nature · 588

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3- 3-dependent cellular localization

2000 · Christina M. Grozinger, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 588

Histone Deacetylase 3 (HDAC3) and Other Class I HDACs Regulate Colon Cell Maturation and p21 Expression and Are Deregulated in Human Colon Cancer

2006 · Andrew J. Wilson, Do-Sun Byun, et al. · Journal of Biological Chemistry · 571

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

2018 · Rachel Fellows, Jérémy Denizot, et al. · Nature Communications · 568

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Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

2011 · Maria M. Mihaylova, Debbie S. Vasquez, et al. · Cell · 563

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Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

2002 · Sung Hee Baek, Kenneth A. Ohgi, et al. · Cell · 558

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Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65

2003 · Rosemary Kiernan, Vanessa Brès, et al. · Journal of Biological Chemistry · 535

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HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

2011 · Susan C. McQuown, Ruth M. Barrett, et al. · Journal of Neuroscience · 505

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Works count: 3,679

Citation count: 124,400