Keyword

HDAC4

Description: HDAC4 is a human gene encoding histone deacetylase 4, a protein involved in regulating gene expression and studied in molecular and disease research.

Primary topic: Histone Deacetylase Inhibitors Research (24%)

Wikidata ID: wiki/Q18034651

OpenAlex ID: keywords/hdac4

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

2005 · Jian-Fu Chen, Elizabeth M Mandel, et al. · Nature Genetics · 2,781

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Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

2000 · Timothy A. McKinsey, Chun-Li Zhang, et al. · Nature · 1,053

Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

2014 · Dalila Pinto, Elsa Delaby, et al. · The American Journal of Human Genetics · 969

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Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis

2004 · Rick B. Vega, Koichi Matsuda, et al. · Cell · 804

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Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 · Christina M. Grozinger, Christian A. Hassig, et al. · Proceedings of the National Academy of Sciences · 764

Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR

2002 · Wolfgang Fischle, Franck Dequiedt, et al. · Molecular Cell · 753

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MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

2009 · Andrew H. Williams, Gregorio Valdez, et al. · Science · 737

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.

2002 · Ryohei Furumai, Akihisa Matsuyama, et al. · PubMed · 732

Class II histone deacetylases: versatile regulators

2003 · Eric Verdin, Franck Dequiedt, et al. · Trends in Genetics · 662

A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue

2013 · Tina Rönn, Petr Volkov, et al. · PLoS Genetics · 619

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The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

2001 · Matthew G. Guenther, Orr Barak, et al. · Molecular and Cellular Biology · 611

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

2009 · Zhaoyong Li, Mohammad Q. Hassan, et al. · Journal of Biological Chemistry · 589

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Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3- 3-dependent cellular localization

2000 · Christina M. Grozinger, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 588

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

2007 · A. Lahm, C. Paolini, et al. · Proceedings of the National Academy of Sciences · 564

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Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

2011 · Maria M. Mihaylova, Debbie S. Vasquez, et al. · Cell · 563

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HDAC4 deacetylase associates with and represses the MEF2 transcription factor

1999 · Eric A. Miska, Christina Karlsson, et al. · The EMBO Journal · 555

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From neural development to cognition: unexpected roles for chromatin

2013 · Jehnna L. Ronan, Wei Wu, et al. · Nature Reviews Genetics · 544

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

2000 · Timothy A. McKinsey, Chun Li Zhang, et al. · Proceedings of the National Academy of Sciences · 517

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

2006 · J. Backs · Journal of Clinical Investigation · 511

MEF2C Transcription Factor Controls Chondrocyte Hypertrophy and Bone Development

2007 · Michael A. Arnold, Yuri Kim, et al. · Developmental Cell · 456

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Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

2010 · Viviana Moresi, Andrew H. Williams, et al. · Cell · 445

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RETRACTED: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis

2008 · Jharna Datta, Huban Kutay, et al. · Cancer Research · 438

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The cartilage specific microRNA‐140 targets histone deacetylase 4 in mouse cells

2006 · Lee Tuddenham, Guy Wheeler, et al. · FEBS Letters · 422

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

2000 · Ryohei Furumai, Yasuhiko Komatsu, et al. · Proceedings of the National Academy of Sciences · 411

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Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

2009 · B Song, Y Wang, et al. · Oncogene · 410

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Works count: 2,488

Citation count: 84,610