Keyword

HDAC5

Description: HDAC5 is a human protein-coding gene that encodes histone deacetylase 5, an enzyme involved in regulating gene expression.

Primary topic: Histone Deacetylase Inhibitors Research (28%)

Wikidata ID: wiki/Q18034954

OpenAlex ID: keywords/hdac5

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

2006 · Nadia M Tsankova, Olivier Berton, et al. · Nature Neuroscience · 1,780

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

2000 · Timothy A. McKinsey, Chun-Li Zhang, et al. · Nature · 1,053

Decreased Histone Deacetylase Activity in Chronic Obstructive Pulmonary Disease

2005 · Kazuhiro Ito, Misako Ito, et al. · New England Journal of Medicine · 970

PDF

Three proteins define a class of human histone deacetylases related to yeast Hda1p

1999 · Christina M. Grozinger, Christian A. Hassig, et al. · Proceedings of the National Academy of Sciences · 764

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

2009 · Fernando Rivadeneira, Karol Estrada, et al. · Nature Genetics · 706

Histone Deacetylases 5 and 9 Govern Responsiveness of the Heart to a Subset of Stress Signals and Play Redundant Roles in Heart Development

2004 · Shurong Chang, Timothy A. McKinsey, et al. · Molecular and Cellular Biology · 613

Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli

2007 · William Renthal, Ian Maze, et al. · Neuron · 599

PDF

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3- 3-dependent cellular localization

2000 · Christina M. Grozinger, Stuart L. Schreiber · Proceedings of the National Academy of Sciences · 588

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

2007 · A. Lahm, C. Paolini, et al. · Proceedings of the National Academy of Sciences · 564

PDF

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

2011 · Maria M. Mihaylova, Debbie S. Vasquez, et al. · Cell · 563

PDF

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

2000 · Timothy A. McKinsey, Chun Li Zhang, et al. · Proceedings of the National Academy of Sciences · 517

Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5

2004 · Rick B. Vega, Brooke C. Harrison, et al. · Molecular and Cellular Biology · 511

Integration of Long-Term-Memory-Related Synaptic Plasticity Involves Bidirectional Regulation of Gene Expression and Chromatin Structure

2002 · Zhonghui Guan, Maurizio Giustetto, et al. · Cell · 496

PDF

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

2009 · Hui Li, Hui Xie, et al. · Journal of Clinical Investigation · 463

AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5

2008 · Sean L. McGee, Bryce J.W. van Denderen, et al. · Diabetes · 453

PDF

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

2010 · Viviana Moresi, Andrew H. Williams, et al. · Cell · 445

PDF

The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

2009 · Johannes Backs, Thea Backs, et al. · Proceedings of the National Academy of Sciences · 432

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

2000 · Hung-Ying Kao, Michael Downes, et al. · Genes & Development · 424

PDF

Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5

2003 · Michael P. Czubryt, John McAnally, et al. · Proceedings of the National Academy of Sciences · 417

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors

2005 · C A Bradbury, F L Khanim, et al. · Leukemia · 404

The histone deacetylase-3 complex contains nuclear receptor corepressors

2000 · Yu-Der Wen, Valentina Perissi, et al. · Proceedings of the National Academy of Sciences · 378

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

2013 · Mercedes Lobera, Kevin P Madauss, et al. · Nature Chemical Biology · 376

Exercise impacts brain‐derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation

2010 · F. Gomez‐Pinilla, Y. Zhuang, et al. · European Journal of Neuroscience · 367

PDF

Repression of Runx2 function by TGF‐β through recruitment of class II histone deacetylases by Smad3

2005 · Jong Seok Kang, Tamara Alliston, et al. · The EMBO Journal · 344

Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation

2006 · Eun-Joo Jeon, Kwang-Youl Lee, et al. · Journal of Biological Chemistry · 343

PDF

Works count: 1,327

Citation count: 48,820