Keyword

HLA-E

Description: HLA-E is a nonclassical major histocompatibility complex class I protein that presents peptides and modulates immune-cell activity in humans.

Primary topic: Immune Cell Function and Interaction (35%)

Wikidata ID: wiki/Q14907768

OpenAlex ID: keywords/hla-e

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 · Veronique M. Braud, David S. J. Allan, et al. · Nature · 2,229

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 · Ni Lee, Manuel Llano, et al. · Proceedings of the National Academy of Sciences · 1,053

Imprint of human cytomegalovirus infection on the NK cell receptor repertoire

2004 · Mónica Gumá, Ana Angulo, et al. · Blood · 865

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The Selective Downregulation of Class I Major Histocompatibility Complex Proteins by HIV-1 Protects HIV-Infected Cells from NK Cells

1999 · George B Cohen, Rajesh T Gandhi, et al. · Immunity · 861

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Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 · Francisco Borrego, Matthias Ulbrecht, et al. · The Journal of Experimental Medicine · 727

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A Human Histocompatibility Leukocyte Antigen (HLA)-G–specific Receptor Expressed on All Natural Killer Cells

1999 · Sumati Rajagopalan, Eric O. Long · The Journal of Experimental Medicine · 726

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Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions

2006 · Shuen-Iu Hung, Wen-Hung Chung, et al. · Pharmacogenetics and Genomics · 680

Surface Expression of HLA-E, an Inhibitor of Natural Killer Cells, Enhanced by Human Cytomegalovirus gpUL40

2000 · Peter Tomasec, Veronique M. Braud, et al. · Science · 662

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells

2017 · Germán G Gornalusse, Roli K Hirata, et al. · Nature Biotechnology · 634

Association of DAP12 with Activating CD94/NKG2C NK Cell Receptors

1998 · Lewis L Lanier, Brian Corliss, et al. · Immunity · 559

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Human NK cells: surface receptors, inhibitory checkpoints, and translational applications

2019 · Simona Sivori, Paola Vacca, et al. · Cellular and Molecular Immunology · 556

Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition

2019 · Branca I. Pereira, Oliver P. Devine, et al. · Nature Communications · 554

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HLA-E Surface Expression Depends on Binding of TAP-Dependent Peptides Derived from Certain HLA Class I Signal Sequences

1998 · Ni Lee, David R Goodlett, et al. · The Journal of Immunology · 505

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

1997 · Veronique Braud, E. Yvonne Jones, et al. · European Journal of Immunology · 502

HLA-E is expressed on trophoblast and interacts with CD94 / NKG2 receptors on decidual NK cells

2000 · Ashley King, David S. J. Allan, et al. · European Journal of Immunology · 416

Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2‐A and the activating receptor CD94/NKG2‐C to HLA‐E

1999 · Mar Valés‐Gómez, Hugh T. Reyburn, et al. · The EMBO Journal · 384

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

1998 · Manuel Llano, Ni Lee, et al. · European Journal of Immunology · 382

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Protein Expression and Peptide Binding Suggest Unique and Interacting Functional Roles for HLA-E, F, and G in Maternal-Placental Immune Recognition

2003 · Akiko Ishitani, Noriko Sageshima, et al. · The Journal of Immunology · 377

The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells

1999 · Francisco Navarro, Manuel Llano, et al. · European Journal of Immunology · 366

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Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti‐HLA antibodies

2008 · Richard Apps, Shawn P. Murphy, et al. · Immunology · 360

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Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells

2019 · Takahiro Kamiya, See Voon Seow, et al. · Journal of Clinical Investigation · 344

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Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

1987 · M C Carroll, P Katzman, et al. · Proceedings of the National Academy of Sciences · 344

NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

2018 · Nadine van Montfoort, Linda Borst, et al. · Cell · 333

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HLA-G in human reproduction: aspects of genetics, function and pregnancy complications

2005 · Thomas Vauvert F. Hviid · Human Reproduction Update · 332

Analysis of regulatory CD8 T cells in Qa-1-deficient mice

2004 · Dan Hu, Koichi Ikizawa, et al. · Nature Immunology · 330

Works count: 2,503

Citation count: 68,990