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HSF1
Description:
Heat shock factor 1, a stress-responsive transcription factor that regulates genes involved in cellular protection and protein homeostasis.
Primary topic:
Heat shock proteins research (41%)
Related topics:
Heat shock proteins research (41%),
Genetics, Aging, and Longevity in Model Organisms (9%)
OpenAlex ID:
keywords/hsf1
Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor
2003
·
Ao-Lin Hsu
, Coleen T. Murphy
, et al.
·
Science
·
1,513
Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1
1998
·
Jiangying Zou
, Yongle Guo
, et al.
·
Cell
·
1,232
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
2001
·
LILA PIRKKALA
, PÄIVI NYKÄNEN
, et al.
·
The FASEB Journal
·
1,009
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
2012
·
Len Neckers
, Paul Workman
·
Clinical Cancer Research
·
958
Regulation of heat shock transcription factors and their roles in physiology and disease
2017
·
Rocio Gomez-Pastor
, Eileen T. Burchfiel
, et al.
·
Nature Reviews Molecular Cell Biology
·
854
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
·
H. Susana Marinho
, Carla Real
, et al.
·
Redox Biology
·
850
PDF
&cestflwr; Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
2001
·
Lutz Nover
, Kapil Bharti
, et al.
·
Cell Stress and Chaperones
·
770
HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers
2012
·
Marc L. Mendillo
, Sandro Santagata
, et al.
·
Cell
·
695
PDF
Molecularchaperones as HSF1-specific transcriptional repressors
1998
·
Y. Shi
, D. D. Mosser
, et al.
·
Genes & Development
·
655
PDF
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
2009
·
Anat Ben-Zvi
, Elizabeth A. Miller
, et al.
·
Proceedings of the National Academy of Sciences
·
649
PDF
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
2007
·
Chad A. Dickey
, Adeela Kamal
, et al.
·
Journal of Clinical Investigation
·
642
PDF
Crosstalk between Components of Circadian and Metabolic Cycles in Mammals
2011
·
Gad Asher
, Ueli Schibler
·
Cell Metabolism
·
601
PDF
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
2009
·
Eric L. Greer
, Anne Brunet
·
Aging Cell
·
572
PDF
HSF1 is required for extra‐embryonic development, postnatal growth and protection during inflammatory responses in mice
1999
·
XianZhong Xiao
, XiaoXia Zuo
, et al.
·
The EMBO Journal
·
550
PDF
Targeted Disruption of Heat Shock Transcription Factor 1 Abolishes Thermotolerance and Protection against Heat-inducible Apoptosis
1998
·
D. Randy McMillan
, Xianzhong Xiao
, et al.
·
Journal of Biological Chemistry
·
524
PDSM, a motif for phosphorylation-dependent SUMO modification
2005
·
Ville Hietakangas
, Julius Anckar
, et al.
·
Proceedings of the National Academy of Sciences
·
501
Regulation of Heat Shock Factor Trimer Formation: Role of a Conserved Leucine Zipper
1993
·
Sridhar K. Rabindran
, Raymond I. Haroun
, et al.
·
Science
·
494
Molecular cloning and expression of a human heat shock factor, HSF1.
1991
·
S K Rabindran
, G Giorgi
, et al.
·
Proceedings of the National Academy of Sciences
·
467
Displacement of sequence-specific transcription factors from mitotic chromatin
1995
·
Marian A. Martínez-Balbás
, Anup Dey
, et al.
·
Cell
·
454
Redox regulation of mammalian heat shock factor 1 is essential for Hsp gene activation and protection from stress
2003
·
Sang-Gun Ahn
, Dennis J. Thiele
·
Genes & Development
·
450
A Developmental Timing MicroRNA and Its Target Regulate Life Span in C. elegans
2005
·
Michelle Boehm
, Frank Slack
·
Science
·
449
The Heat Shock Response: Systems Biology of Proteotoxic Stress in Aging and Disease
2011
·
R. I. Morimoto
·
Cold Spring Harbor Symposia on Quantitative Biology
·
408
PDF
Isolation of the gene encoding the S. cerevisiae heat shock transcription factor
1988
·
Greg Wiederrecht
, Donald Seto
, et al.
·
Cell
·
408
Glucose Shortens the Life Span of C. elegans by Downregulating DAF-16/FOXO Activity and Aquaporin Gene Expression
2009
·
Seung-Jae Lee
, Coleen T. Murphy
, et al.
·
Cell Metabolism
·
394
PDF
HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
2007
·
Cyril Boyault
, Yu Zhang
, et al.
·
Genes & Development
·
368
PDF
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Works count:
3,498
Citation count:
91,280
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