Keyword

hyperalgesia

Description: An abnormally increased sensitivity to painful stimuli, studied in pain research and clinical medicine.

Primary topic: Pain Mechanisms and Treatments (55%)

Wikidata ID: wiki/Q1633866

OpenAlex ID: keywords/hyperalgesia

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 · Gary J. Bennett, Y.-K. Xie · Pain · 5,366

Central sensitization: Implications for the diagnosis and treatment of pain

2010 · Clifford J. Woolf · Pain · 4,755

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

2009 · Alban Latremoliere, Clifford J. Woolf · Journal of Pain · 3,903

Neuronal Plasticity: Increasing the Gain in Pain

2000 · Clifford J. Woolf, Michael W. Salter · Science · 3,789

Opioid Complications and Side Effects

2008 · Ramsin Benyamin · Pain Physician · 2,268

Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

1993 · Terence J. Coderre, Joel Katz, et al. · Pain · 1,970

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TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents

2006 · Diana M. Bautista, Sven-Eric Jordt, et al. · Cell · 1,935

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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1995 · Jean-Claude Meunier, Catherine Mollereau, et al. · Nature · 1,914

Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor

1995 · Rainer K. Reinscheid, Hans-Peter Nothacker, et al. · Science · 1,823

Glutamate as a Neurotransmitter in the Brain: Review of Physiology and Pathology

2000 · Brian S. Meldrum · Journal of Nutrition · 1,661

Animal Models of Nociception

2006 · Ildikó Rácz, Andreas Zimmer · 1,659

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain

2018 · Ru-Rong Ji, Andrea Nackley, et al. · Anesthesiology · 1,624

The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway

2001 · Michael J Caterina, David Julius · Annual Review of Neuroscience · 1,576

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

2003 · Makoto Tsuda, Yukari Shigemoto-Mogami, et al. · Nature · 1,565

Neuronal circuitry for pain processing in the dorsal horn

2010 · Andrew J. Todd · Nature reviews. Neuroscience · 1,476

Development and validation of the Neuropathic Pain Symptom Inventory

2004 · Didier Bouhassira, Nadine Attal, et al. · Pain · 1,338

TRPA1 mediates formalin-induced pain

2007 · Colleen R. McNamara, Josh Mandel-Brehm, et al. · Proceedings of the National Academy of Sciences · 1,265

Models and Mechanisms of Hyperalgesia and Allodynia

2009 · Jürgen Sandkühler · Physiological Reviews · 1,149

Sex differences in pain

1997 · Karen J. Berkley · Behavioral and Brain Sciences · 1,124

Role of the Immune system in chronic pain

2005 · Fabien Marchand, Mauro Perretti, et al. · Nature reviews. Neuroscience · 1,098

What we know about primary dysmenorrhea today: a critical review

2015 · Stella Iacovides, Ingrid Avidon, et al. · Human Reproduction Update · 1,024

Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes

2010 · C. Maier, R. Baron, et al. · Pain · 1,021

Allodynia and hyperalgesia in neuropathic pain: clinical manifestations and mechanisms

2014 · Troels S Jensen, Nanna B Finnerup · The Lancet Neurology · 976

Pathobiology of neuropathic pain

2001 · Manfred Zimmermann · European Journal of Pharmacology · 937

Activity-dependent neuronal plasticity following tissue injury and inflammation

1992 · R. Dubner, M.A. Ruda · Trends in Neurosciences · 926

Works count: 13,810

Citation count: 474,200