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Keyword

hyperinflammation

Description: An excessive or dysregulated inflammatory immune response, studied in conditions such as severe infections and COVID-19.
OpenAlex ID: keywords/hyperinflammation
COVID-19: consider cytokine storm syndromes and immunosuppression
2020 · Puja Mehta, Daniel F McAuley, et al. · The Lancet · 9,662
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The pathogenesis and treatment of the `Cytokine Storm' in COVID-19
2020 · Qing Ye, Bili Wang, et al. · Journal of Infection · 2,759
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Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 · Richard S. Hotchkiss, Guillaume Monneret, et al. · Nature reviews. Immunology · 2,734
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An inflammatory cytokine signature predicts COVID-19 severity and survival
2020 · Diane Marie Del Valle, Seunghee Kim-Schulze, et al. · Nature Medicine · 2,595
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Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
2020 · Miriam Merad, Jerome C. Martin · Nature reviews. Immunology · 2,468
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Neurological associations of COVID-19
2020 · Mark A Ellul, Laura Benjamin, et al. · The Lancet Neurology · 2,153
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Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
2020 · Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea, et al. · Cell Host & Microbe · 2,043
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Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
2011 · Jonathan S. Boomer, Kathleen To, et al. · JAMA · 1,784
The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease
2020 · Dennis McGonagle, Kassem Sharif, et al. · Autoimmunity Reviews · 1,653
Extracellular histones are major mediators of death in sepsis
2009 · Jun Xu, Xiaomei Zhang, et al. · Nature Medicine · 1,541
Efficacy of Tocilizumab in Patients Hospitalized with Covid-19
2020 · John H. Stone, Matthew J. Frigault, et al. · New England Journal of Medicine · 1,362
Multisystem Inflammatory Syndrome in Children in New York State
2020 · Elizabeth M. Dufort, Emilia H. Koumans, et al. · New England Journal of Medicine · 1,352
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Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
2020 · Carlos Salama, Jian Han, et al. · New England Journal of Medicine · 1,291
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Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome
2004 · C K WONG, C W K LAM, et al. · Clinical & Experimental Immunology · 1,274
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Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
2020 · Tobias Herold, Vindi Jurinovic, et al. · Journal of Allergy and Clinical Immunology · 1,158
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How I treat hemophagocytic lymphohistiocytosis
2011 · Michael B. Jordan, Carl E. Allen, et al. · Blood · 1,148
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Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia
2021 · Ivan O. Rosas, Norbert Bräu, et al. · New England Journal of Medicine · 1,125
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COVID-19: combining antiviral and anti-inflammatory treatments
2020 · Justin Stebbing, Anne Phelan, et al. · The Lancet Infectious Diseases · 1,115
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Recommendations for the management of hemophagocytic lymphohistiocytosis in adults
2019 · Paul La Rosée, AnnaCarin Horne, et al. · Blood · 1,112
Diabetes mellitus and periodontitis: a tale of two common interrelated diseases
2011 · Evanthia Lalla, Panos N. Papapanou · Nature Reviews Endocrinology · 1,048
COVID-19 and Multiorgan Response
2020 · Sevim Zaim, Jun Heng Chong, et al. · Current Problems in Cardiology · 1,022
The immunology of sepsis
2021 · Tom van der Poll, Manu Shankar-Hari, et al. · Immunity · 1,017
Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study
2020 · Giulio Cavalli, Giacomo De Luca, et al. · The Lancet Rheumatology · 970
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Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
2020 · Jeong Seok Lee, Seongwan Park, et al. · Science Immunology · 826
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Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
2020 · Panagiotis Skendros, Alexandros Mitsios, et al. · Journal of Clinical Investigation · 785
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Works count: 8,465
Citation count: 215,900
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