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Keyword

IKK complex

Description: A protein complex that regulates NF-κB signaling by phosphorylating inhibitors of NF-κB in response to cellular signals.
Wikidata ID: wiki/Q107517496
OpenAlex ID: keywords/ikk-complex
Signaling via the NFκB system
2016 · Simon Mitchell, Jesse Vargas, et al. · WIREs Systems Biology and Medicine · 1,030
The IKK Complex, a Central Regulator of NF- B Activation
2009 · A. Israel · Cold Spring Harbor Perspectives in Biology · 849
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X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling
2001 · Rainer Döffinger, Asma Smahi, et al. · Nature Genetics · 828
IκB Kinases Phosphorylate NF-κB p65 Subunit on Serine 536 in the Transactivation Domain
1999 · Hiroaki Sakurai, Hiroaki Chiba, et al. · Journal of Biological Chemistry · 824
Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex
2000 · Michael J. May, Fulvio D'Acquisto, et al. · Science · 680
CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri
2001 · Stephen E Girardin, Régis Tournebize, et al. · EMBO Reports · 609
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A critical role of RICK/RIP2 polyubiquitination in Nod‐induced NF‐κB activation
2007 · Mizuho Hasegawa, Yukari Fujimoto, et al. · The EMBO Journal · 523
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The Role of Ubiquitin in NF-κB Regulatory Pathways
2009 · Brian Skaug, Xiaomo Jiang, et al. · Annual Review of Biochemistry · 470
NLRC5 Negatively Regulates the NF-κB and Type I Interferon Signaling Pathways
2010 · Jun Cui, Liang Zhu, et al. · Cell · 448
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Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor
2005 · Helen Su, Nicolas Bidère, et al. · Science · 429
TNF-Induced Recruitment and Activation of the IKK Complex Require Cdc37 and Hsp90
2002 · Guoqing Chen, Ping Cao, et al. · Molecular Cell · 400
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The IKK complex: an integrator of all signals that activate NF-κB?
2000 · Alain Israël · Trends in Cell Biology · 398
Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling
2003 · Jürgen Ruland, Gordon S Duncan, et al. · Immunity · 390
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Tumor Necrosis Factor-α-induced IKK Phosphorylation of NF-κB p65 on Serine 536 Is Mediated through the TRAF2, TRAF5, and TAK1 Signaling Pathway
2003 · Hiroaki Sakurai, Shunsuke Suzuki, et al. · Journal of Biological Chemistry · 377
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-κB-dependent innate immune responses
2001 · Sheila Vidal, Ranjiv S. Khush, et al. · Genes & Development · 313
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The IKK complex contributes to the induction of autophagy
2009 · Alfredo Criollo, Laura Senovilla, et al. · The EMBO Journal · 296
A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation
2010 · Michael Hinz, Michael Stilmann, et al. · Molecular Cell · 280
The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia
2010 · Lluis Espinosa, Severine Cathelin, et al. · Cancer Cell · 266
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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage
2010 · Shigeki Miyamoto · Cell Research · 253
The Transcription Factor Nuclear Factor-kappa B and Cancer
2007 · R.O. Escárcega, S. Fuentes-Alexandro, et al. · Clinical Oncology · 237
CARD9 Is a Novel Caspase Recruitment Domain-containing Protein That Interacts With BCL10/CLAP and Activates NF-κB
2000 · John Bertin, Yin Guo, et al. · Journal of Biological Chemistry · 231
NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer
2015 · Collin M. Blakely, Evangelos Pazarentzos, et al. · Cell Reports · 204
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NEMO specifically recognizes K63‐linked poly‐ubiquitin chains through a new bipartite ubiquitin‐binding domain
2009 · E Laplantine, E Fontan, et al. · The EMBO Journal · 201
The IκB Kinase (IKK) Inhibitor, NEMO-binding Domain Peptide, Blocks Osteoclastogenesis and Bone Erosion in Inflammatory Arthritis
2004 · Simon Dai, Teruhisa Hirayama, et al. · Journal of Biological Chemistry · 196
Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL
2021 · Anja Schmitt, Wendan Xu, et al. · Blood · 193
Works count: 407
Citation count: 19,280
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