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Keyword

IKKα

Description: IKKα, also known as IκB kinase alpha, is a protein kinase subunit involved in NF-κB signaling and regulation of gene expression.
OpenAlex ID: keywords/ikkalpha
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 · Michael Karin, Yinon Ben-Neriah · Annual Review of Immunology · 4,764
The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation
1997 · Ebrahim Zandi, David M Rothwarf, et al. · Cell · 1,812
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Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
2004 · Jong Sung Park, Daiva Svetkauskaite, et al. · Journal of Biological Chemistry · 1,562
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Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway
2001 · Uwe Senftleben, Yixue Cao, et al. · Science · 1,359
Regulation and Function of IKK and IKK-Related Kinases
2006 · Hans Häcker, Michael Karin · Science s STKE · 1,274
Identification and Characterization of an IκB Kinase
1997 · Catherine H Régnier, Ho Yeong Song, et al. · Cell · 1,174
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How NF-κB is activated: the role of the IκB kinase (IKK) complex
1999 · Michael Karin · Oncogene · 1,156
IKK-γ is an essential regulatory subunit of the IκB kinase complex
1998 · David M. Rothwarf, Ebrahim Zandi, et al. · Nature · 957
The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
2000 · Michael Karin, Mireille Delhase · Seminars in Immunology · 955
The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis
1999 · Zhi-Wei Li, Wenming Chu, et al. · The Journal of Experimental Medicine · 926
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The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
2002 · Emmanuel Dejardin, Nathalie M Droin, et al. · Immunity · 922
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Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation
1999 · Mireille Delhase, Makio Hayakawa, et al. · Science · 852
The IKK Complex, a Central Regulator of NF- B Activation
2009 · A. Israel · Cold Spring Harbor Perspectives in Biology · 849
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Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase
1999 · Yinling Hu, Véronique Baud, et al. · Science · 823
The noncanonical NF‐κB pathway
2012 · Shao‐Cong Sun · Immunological Reviews · 722
BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells
2002 · Estefania Claudio, Keith Brown, et al. · Nature Immunology · 693
Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex
2000 · Michael J. May, Fulvio D'Acquisto, et al. · Science · 680
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling
2011 · Wei Tan, Weizhou Zhang, et al. · Nature · 647
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
2005 · Toby Lawrence, Magali Bebien, et al. · Nature · 626
Limb and Skin Abnormalities in Mice Lacking IKKα
1999 · Kiyoshi Takeda, Osamu Takeuchi, et al. · Science · 609
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
2003 · Yumi Yamamoto, Udit N. Verma, et al. · Nature · 577
The IκB kinase complex in NF‐κB regulation and beyond
2013 · Michael Hinz, Claus Scheidereit · EMBO Reports · 571
Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice
1999 · Masato Tanaka, Maria Elena Fuentes, et al. · Immunity · 569
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NF-κB Signaling: Multiple Angles to Target OA
2010 · Kenneth B. Marcu, Miguel Otero, et al. · Current Drug Targets · 565
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
1998 · Lei Ling, Zhaodan Cao, et al. · Proceedings of the National Academy of Sciences · 535
Works count: 1,603
Citation count: 75,230
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