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Keyword

IKKβ

Description: IKKβ is a protein kinase subunit of the IκB kinase complex, which regulates NF-κB signaling in immune and inflammatory responses.
OpenAlex ID: keywords/ikkbeta
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 · Michael Karin, Yinon Ben-Neriah · Annual Review of Immunology · 4,764
NF-κB: linking inflammation and immunity to cancer development and progression
2005 · Michael Karin, Florian R. Greten · Nature reviews. Immunology · 3,086
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 · Florian R. Greten, Lars Eckmann, et al. · Cell · 2,431
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Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
2005 · Dongsheng Cai, Minsheng Yuan, et al. · Nature Medicine · 2,242
The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation
1997 · Ebrahim Zandi, David M Rothwarf, et al. · Cell · 1,812
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IKK-β links inflammation to obesity-induced insulin resistance
2005 · Melek C Arkan, Andrea L Hevener, et al. · Nature Medicine · 1,770
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
2008 · Jordi Rius, Monica Guma, et al. · Nature · 1,612
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The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
1998 · Min-Jean Yin, Yumi Yamamoto, et al. · Nature · 1,590
Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
2004 · Jong Sung Park, Daiva Svetkauskaite, et al. · Journal of Biological Chemistry · 1,562
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IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice
2004 · Dongsheng Cai, J.Daniel Frantz, et al. · Cell · 1,366
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Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity
2008 · Xiaoqing Zhang, Guo Zhang, et al. · Cell · 1,347
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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
2006 · Koei Chin, Sandy DeVries, et al. · Cancer Cell · 1,317
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Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
2000 · Antonio Rossi, Pankaj Kapahi, et al. · Nature · 1,310
Regulation and Function of IKK and IKK-Related Kinases
2006 · Hans Häcker, Michael Karin · Science s STKE · 1,274
NF-κB and STAT3 – key players in liver inflammation and cancer
2010 · Guobin He, Michael Karin · Cell Research · 1,197
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IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis
2005 · Shin Maeda, Hideaki Kamata, et al. · Cell · 1,164
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How NF-κB is activated: the role of the IκB kinase (IKK) complex
1999 · Michael Karin · Oncogene · 1,156
Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene
1999 · Qiutang Li, Daniel Van Antwerp, et al. · Science · 963
IKK-γ is an essential regulatory subunit of the IκB kinase complex
1998 · David M. Rothwarf, Ebrahim Zandi, et al. · Nature · 957
The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
2000 · Michael Karin, Mireille Delhase · Seminars in Immunology · 955
Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease
2003 · Zhiping Li, Shiqi Yang, et al. · Hepatology · 930
The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
2002 · Emmanuel Dejardin, Nathalie M Droin, et al. · Immunity · 922
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Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation
1999 · Mireille Delhase, Makio Hayakawa, et al. · Science · 852
The IKK Complex, a Central Regulator of NF- B Activation
2009 · A. Israel · Cold Spring Harbor Perspectives in Biology · 849
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Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
2013 · Guo Zhang, Juxue Li, et al. · Nature · 834
Works count: 3,684
Citation count: 161,500
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