Keyword

interferon lambda

Description: A type III interferon cytokine that regulates antiviral and immune responses, particularly at epithelial and mucosal surfaces.

Primary topic: interferon and immune responses (31%)

Wikidata ID: wiki/Q12745567

OpenAlex ID: keywords/interferon-lambda

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

2020 · Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, et al. · Cell · 4,214

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Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

2020 · Jérôme Hadjadj, Nader Yatim, et al. · Science · 2,981

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Autoantibodies against type I IFNs in patients with life-threatening COVID-19

2020 · Paul Bastard, Lindsey B. Rosen, et al. · Science · 2,657

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

2020 · Qian Zhang, Paul Bastard, et al. · Science · 2,227

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

2009 · David L. Thomas, Chloe L. Thio, et al. · Nature · 2,150

IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex

2002 · Sergei V. Kotenko, Grant Gallagher, et al. · Nature Immunology · 1,868

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

2009 · for the Hepatitis C Study, Vijayaprakash Suppiah, et al. · Nature Genetics · 1,826

CDK4/6 inhibition triggers anti-tumour immunity

2017 · Shom Goel, Molly J. DeCristo, et al. · Nature · 1,506

Shared and Distinct Functions of Type I and Type III Interferons

2019 · Helen M. Lazear, John W. Schoggins, et al. · Immunity · 1,139

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Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

2010 · Andri Rauch, Zoltán Kutalik, et al. · Gastroenterology · 1,137

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

2022 · Chansavath Phetsouphanh, David R. Darley, et al. · Nature Immunology · 1,018

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Role of deficient type III interferon-λ production in asthma exacerbations

2006 · Marco Contoli, Simon D Message, et al. · Nature Medicine · 1,008

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

2020 · Annsea Park, Akiko Iwasaki · Cell Host & Microbe · 908

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INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

2012 · Irina Rusinova, Sam Forster, et al. · Nucleic Acids Research · 876

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IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

2008 · Caroline Sommereyns, Sophie Paul, et al. · PLoS Pathogens · 774

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A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

2020 · Kenneth H. Dinnon, Sarah R. Leist, et al. · Nature · 674

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Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo

2006 · Nina Ank, Hans West, et al. · Journal of Virology · 598

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Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics

2006 · Tobias Marcello, Arash Grakoui, et al. · Gastroenterology · 562

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The interferon system of teleost fish

2005 · Børre Robertsen · Fish & Shellfish Immunology · 562

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

2014 · Delphine Goubau, Martin Schlee, et al. · Nature · 555

Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection

2016 · Avraham Bayer, Nicholas J. Lennemann, et al. · Cell Host & Microbe · 547

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Decoding type I and III interferon signalling during viral infection

2019 · Emily V. Mesev, Robert A. LeDesma, et al. · Nature Microbiology · 535

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection

2020 · Jack Major, Stefania Crotta, et al. · Science · 504

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Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison

2020 · Ioanna-Evdokia Galani, Nikoletta Rovina, et al. · Nature Immunology · 501

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Viral infection and Toll‐like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte‐derived dendritic cells

2004 · Eliana M. Coccia, Martina Severa, et al. · European Journal of Immunology · 490

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Works count: 8,018

Citation count: 144,100