Keyword

IRF7

Description: IRF7 is a human gene encoding a transcription factor that regulates antiviral immune responses, especially the production of type I interferons.

Primary topic: interferon and immune responses (37%)

Wikidata ID: wiki/Q18028003

OpenAlex ID: keywords/irf7

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

2007 · Luke A. J. O'Neill, Andrew G. Bowie · Nature reviews. Immunology · 2,675

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

2005 · Taro Kawai, Ken Takahashi, et al. · Nature Immunology · 2,561

IRF-7 is the master regulator of type-I interferon-dependent immune responses

2005 · Kenya Honda, Hideyuki Yanai, et al. · Nature · 2,249

Triggering the Interferon Antiviral Response Through an IKK-Related Pathway

2003 · Sonia Sharma, Benjamin R. tenOever, et al. · Science · 1,664

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

2015 · David Roulois, Helen Loo Yau, et al. · Cell · 1,515

PDF

Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

2000 · Mitsuharu Sato, Hirofumi Suemori, et al. · Immunity · 1,339

PDF

Regulation and Function of IKK and IKK-Related Kinases

2006 · Hans Häcker, Michael Karin · Science s STKE · 1,274

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF

2003 · Katherine A. Fitzgerald, Daniel C. Rowe, et al. · The Journal of Experimental Medicine · 1,193

PDF

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

2013 · Alex K. Shalek, Rahul Satija, et al. · Nature · 1,187

Differential viral induction of distinct interferon‐α genes by positive feedback through interferon regulatory factor‐7

1998 · Isabelle Marié, Joan E. Durbin, et al. · The EMBO Journal · 1,049

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

2004 · Taro Kawai, Shintaro Sato, et al. · Nature Immunology · 1,035

A Mouse Model of Zika Virus Pathogenesis

2016 · Helen M. Lazear, Jennifer Govero, et al. · Cell Host & Microbe · 908

PDF

Presence of Genetic Variants Among Young Men With Severe COVID-19

2020 · Caspar I. van der Made, Annet Simons, et al. · JAMA · 788

PDF

Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo

1998 · Marc G Wathelet, Charles H Lin, et al. · Molecular Cell · 733

PDF

Transcription Factor E2-2 Is an Essential and Specific Regulator of Plasmacytoid Dendritic Cell Development

2008 · Babacar Cisse, Michele L. Caton, et al. · Cell · 672

PDF

An Atomic Model of the Interferon-β Enhanceosome

2007 · Daniel Panne, Tom Maniatis, et al. · Cell · 624

PDF

How Toll-like receptors signal: what we know and what we don’t know

2005 · Luke AJ O’Neill · Current Opinion in Immunology · 614

IRF7: activation, regulation, modification and function

2011 · S Ning, J S Pagano, et al. · Genes and Immunity · 604

PDF

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

2008 · Denis Gaucher, René Therrien, et al. · The Journal of Experimental Medicine · 595

PDF

Interferon regulatory factors: the next generation

1999 · Yael Mamane, Christophe Heylbroeck, et al. · Gene · 579

Toll-Like Receptor 4 Is Involved in the Development of Fructose-Induced Hepatic Steatosis in Mice†

2009 · Astrid Spruss, Giridhar Kanuri, et al. · Hepatology · 562

PDF

Positive feedback regulation of type I IFN genes by the IFN‐inducible transcription factor IRF‐7

1998 · Mitsuharu Sato, Naoki Hata, et al. · FEBS Letters · 553

PDF

A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells

2005 · Grégory Gautier, Martine Humbert, et al. · The Journal of Experimental Medicine · 537

PDF

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

2004 · Kenya Honda, Hideyuki Yanai, et al. · Proceedings of the National Academy of Sciences · 525

Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma

2012 · Yibin Yang, Arthur L. Shaffer, et al. · Cancer Cell · 521

PDF

Works count: 3,298

Citation count: 116,000