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Keyword

islet function

Description: The physiological activity of pancreatic islets, especially their regulation of blood glucose through insulin and other hormone secretion.
OpenAlex ID: keywords/islet-function
Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1
2018 · Daniel J. Drucker · Cell Metabolism · 2,147
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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships.
1994 · Y Lee, H Hirose, et al. · Proceedings of the National Academy of Sciences · 836
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
2000 · Sarah Ferber, Amir Halkin, et al. · Nature Medicine · 745
Inactivation of specific β cell transcription factors in type 2 diabetes
2013 · Shuangli Guo, Chunhua Dai, et al. · Journal of Clinical Investigation · 518
Diabetes/Metabolism Research and Reviews
2006 · Diabetes/Metabolism Research and Reviews · 511
Islet Function in Offspring of Mothers on Low-Protein Diet During Gestation
1991 · Saloua Dahri, Anne Snoeck, et al. · Diabetes · 443
Functional Subdivision of Islets of Langerhans and Possible Role of D Cells
1975 · Lelio Orci, RogerH Unger · The Lancet · 414
Reduction in Pancreatic Transcription Factor PDX-1 Impairs Glucose-stimulated Insulin Secretion
2002 · Marcela Brissova, Masakazu Shiota, et al. · Journal of Biological Chemistry · 376
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Glucagon-Like Peptide-1 and Exendin-4 Stimulate β-Cell Neogenesis in Streptozotocin-Treated Newborn Rats Resulting in Persistently Improved Glucose Homeostasis at Adult Age
2001 · Cécile Tourrel, Danielle Bailbé, et al. · Diabetes · 362
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Islet inflammation in type 2 diabetes and physiology
2017 · Kosei Eguchi, Ryozo Nagai · Journal of Clinical Investigation · 361
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Pathogenesis of Age-Related Glucose Intolerance in Man: Insulin Resistance and Decreased β-Cell Function*
1985 · M. CHEN, R. N. BERGMAN, et al. · The Journal of Clinical Endocrinology & Metabolism · 352
Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function
2008 · Astrid C. Hauge-Evans, Aileen J. King, et al. · Diabetes · 335
Variables in Organ Donors That Affect the Recovery of Human Islets of Langerhans1
1996 · Jonathan R.T. Lakey, Garth L. Warnock, et al. · Transplantation · 306
Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes
2012 · Carolina E. Hagberg, Annika Mehlem, et al. · Nature · 287
Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity in adults with type 2 diabetes: a multicentre, randomised, double-blind, parallel-arm, phase 1 clinical trial
2022 · Tim Heise, Andrea Mari, et al. · The Lancet Diabetes & Endocrinology · 265
Heavy metals, islet function and diabetes development
2009 · Ya Wen Chen, Ching Yao Yang, et al. · Islets · 249
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans
1995 · Y. P. Zhou · The Journal of Clinical Endocrinology & Metabolism · 245
The Dipeptidyl Peptidase IV Inhibitor Vildagliptin Suppresses Endogenous Glucose Production and Enhances Islet Function after Single-Dose Administration in Type 2 Diabetic Patients
2007 · Bogdan Balas, Muhammad R. Baig, et al. · The Journal of Clinical Endocrinology & Metabolism · 243
A new method of preparation of segmental pancreatic grafts for transplantation: trials in dogs and in man.
1978 · J M Dubernard, J Traeger, et al. · PubMed · 231
Refinement of the Automated Method for Human Islet Isolation and Presentation of a Closed System for In Vitro Islet Culture
2004 · Masafumi Goto, Torsten M. Eich, et al. · Transplantation · 223
Pathophysiology of Insulin Secretion in Non-insulin-dependent Diabetes Mellitus
1984 · W Kenneth Ward, James C Beard, et al. · Diabetes Care · 216
Insulin Resistance and Type 2 Diabetes in High-Fat–Fed Mice Are Linked to High Glycotoxin Intake
2005 · Oana Sandu, Keying Song, et al. · Diabetes · 213
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Islet Graft Assessment in the Edmonton Protocol
2004 · Cale N. Street, Jonathan R.T. Lakey, et al. · Diabetes · 211
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Large-Scale Purification of Human Islets Utilizing Discontinuous Albumin Gradient on IBM 2991 Cell Separator
1989 · Stephen P Lake, P Drew Bassett, et al. · Diabetes · 210
10-year trajectory of β-cell function and insulin sensitivity in the development of type 2 diabetes: a community-based prospective cohort study
2015 · Jung Hun Ohn, Soo Heon Kwak, et al. · The Lancet Diabetes & Endocrinology · 209
Works count: 3,674
Citation count: 51,810
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