Keyword

ketamine

Description: Ketamine is a dissociative anesthetic drug used for anesthesia and pain management and, in some settings, treatment of depression.

Primary topic: Anesthesia and Sedative Agents (21%)

Wikidata ID: wiki/Q243547

OpenAlex ID: keywords/ketamine

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

2013 · Undine E. Lang, Stefan Borgwardt · Cellular Physiology and Biochemistry · 8,475

Antidepressant effects of ketamine in depressed patients

2000 · Robert M Berman, Angela Cappiello, et al. · Biological Psychiatry · 3,851

A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

2006 · Carlos A. Zarate, Jaskaran B. Singh, et al. · Archives of General Psychiatry · 3,761

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Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

1994 · John H. Krystal · Archives of General Psychiatry · 3,326

Recent advances in the phencyclidine model of schizophrenia

1991 · D C Javitt, S R Zukin · American Journal of Psychiatry · 2,904

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

2010 · Nanxin Li, Boyoung Lee, et al. · Science · 2,880

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

2011 · Anita E. Autry, Megumi Adachi, et al. · Nature · 1,926

A novel slow (< 1 Hz) oscillation of neocortical neurons in vivo: depolarizing and hyperpolarizing components

1993 · M Steriade, A Nunez, et al. · Journal of Neuroscience · 1,900

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The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 · E H Wong, J A Kemp, et al. · Proceedings of the National Academy of Sciences · 1,819

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

1997 · Bita Moghaddam, Barbara Adams, et al. · Journal of Neuroscience · 1,791

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Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

2001 · David L. Braff, Mark A. Geyer, et al. · Psychopharmacology · 1,707

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

2012 · Ronald S. Duman, George K. Aghajanian · Science · 1,647

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

2016 · Panos Zanos, Ruin Moaddel, et al. · Nature · 1,607

Ketamine—Its Pharmacology and Therapeutic Uses

1982 · Paul F. white, Walter L. Way, et al. · Anesthesiology · 1,479

The use of c-fos as a metabolic marker in neuronal pathway tracing

1989 · M. Dragunow, R. Faull · Journal of Neuroscience Methods · 1,413

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

1983 · N.A. Anis, S.C. Berry, et al. · British Journal of Pharmacology · 1,399

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Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort

2009 · Robert T. Wilder, Randall P. Flick, et al. · Anesthesiology · 1,365

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Giant synaptic potentials in immature rat CA3 hippocampal neurones.

1989 · Y Ben‐Ari, E Cherubini, et al. · The Journal of Physiology · 1,316

The Neuropsychopharmacology of Phencyclidine From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia

1999 · J Jentsch · Neuropsychopharmacology · 1,314

Development of a rational scale to assess the harm of drugs of potential misuse

2007 · David Nutt, Leslie A King, et al. · The Lancet · 1,304

Opiates and endogenous opioid peptides

1977 · John S. Kelly, Ray Dingledine · Trends in Biochemical Sciences · 1,282

Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

2018 · Panos Zanos, Ruin Moaddel, et al. · Pharmacological Reviews · 1,257

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Pathological Changes Induced in Cerebrocortical Neurons by Phencyclidine and Related Drugs

1989 · John W. Olney, Joann Labruyere, et al. · Science · 1,237

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

2014 · Dawn L. Hershman, Christina Lacchetti, et al. · Journal of Clinical Oncology · 1,210

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Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

2013 · James W. Murrough, Dan V. Iosifescu, et al. · American Journal of Psychiatry · 1,206

Works count: 42,250

Citation count: 734,400