Keyword

KLF4

Description: A gene encoding Krüppel-like factor 4, a transcription factor involved in regulating cell growth, differentiation, and stem-cell properties.

Primary topic: Pluripotent Stem Cells Research (25%)

Wikidata ID: wiki/Q18033993

OpenAlex ID: keywords/klf4

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

2006 · Kazutoshi Takahashi, Shinya Yamanaka · Cell · 26,660

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

2007 · Kazutoshi Takahashi, Koji Tanabe, et al. · Cell · 20,197

Generation of germline-competent induced pluripotent stem cells

2007 · Keisuke Okita, Tomoko Ichisaka, et al. · Nature · 4,305

Reprogramming of human somatic cells to pluripotency with defined factors

2007 · In-Hyun Park, Rui Zhao, et al. · Nature · 2,879

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

2007 · Masato Nakagawa, Michiyo Koyanagi, et al. · Nature Biotechnology · 2,794

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

2007 · Marius Wernig, Alexander Meissner, et al. · Nature · 2,678

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

2008 · Xi Chen, Han Xu, et al. · Cell · 2,500

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

2008 · Keisuke Okita, Masato Nakagawa, et al. · Science · 2,009

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

2009 · Knut Woltjen, Iacovos P. Michael, et al. · Nature · 1,817

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

2009 · Dohoon Kim, Chun-Hyung Kim, et al. · Cell stem cell · 1,813

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Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

2009 · Hongyan Zhou, Shili Wu, et al. · Cell stem cell · 1,788

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Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution

2007 · Nimet Maherali, Rupa Sridharan, et al. · Cell stem cell · 1,726

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

2009 · Ulrich Wellner, Jörg Schubert, et al. · Nature Cell Biology · 1,699

Induced Pluripotent Stem Cells Generated Without Viral Integration

2008 · Matthias Stadtfeld, Masaki Nagaya, et al. · Science · 1,679

miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

2009 · Kimberly R. Cordes, Neil T. Sheehy, et al. · Nature · 1,588

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

2008 · Trond Aasen, Angel Raya, et al. · Nature Biotechnology · 1,422

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

2008 · Danwei Huangfu, Kenji Osafune, et al. · Nature Biotechnology · 1,341

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

2008 · Jonghwan Kim, Jianlin Chu, et al. · Cell · 1,333

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Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

2009 · Hyenjong Hong, Kazutoshi Takahashi, et al. · Nature · 1,301

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

2009 · Keisuke Kaji, Katherine Norrby, et al. · Nature · 1,252

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

2015 · Laura S Shankman, Delphine Gomez, et al. · Nature Medicine · 1,213

Induction of Pluripotent Stem Cells From Adult Human Fibroblasts by Defined Factors

2008 · Kazutoshi Takahashi, Koji Tanabe, et al. · Obstetrical & Gynecological Survey · 1,174

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A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

2010 · Ronghui Li, Jialiang Liang, et al. · Cell stem cell · 1,131

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MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

2009 · Na Xu, Thales Papagiannakopoulos, et al. · Cell · 1,124

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Dynamic changes in the human methylome during differentiation

2010 · Louise Laurent, Eleanor Wong, et al. · Genome Research · 1,041

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Works count: 7,575

Citation count: 304,100