Keyword

KLF8

Description: A human gene that encodes a Krüppel-like zinc-finger transcription factor involved in regulating gene expression and studied in cancer biology.

Primary topic: Kruppel-like factors research (58%)

Wikidata ID: wiki/Q18036454

OpenAlex ID: keywords/klf8

Krüppel-like Factors: Three Fingers in Many Pies

2001 · James J. Bieker · Journal of Biological Chemistry · 605

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Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm

2016 · Li-Fang Chu, Ning Leng, et al. · Genome biology · 475

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Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

2012 · Xiaolei Zhang, Peibin Yue, et al. · Proceedings of the National Academy of Sciences · 344

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New concepts regarding focal adhesion kinase promotion of cell migration and proliferation

2006 · Braden D. Cox, Meera Natarajan, et al. · Journal of Cellular Biochemistry · 291

XLID-Causing Mutations and Associated Genes Challenged in Light of Data From Large-Scale Human Exome Sequencing

2013 · Amélie Piton, Claire Redin, et al. · The American Journal of Human Genetics · 257

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Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia

2016 · Lili Wang, Angela N. Brooks, et al. · Cancer Cell · 208

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Kruppel-Like Factor 8 Induces Epithelial to Mesenchymal Transition and Epithelial Cell Invasion

2007 · Xianhui Wang, Mingzhe Zheng, et al. · Cancer Research · 191

Identification of Transcription Factor KLF8 as a Downstream Target of Focal Adhesion Kinase in Its Regulation of Cyclin D1 and Cell Cycle Progression

2003 · Jihe Zhao, Z.Christine Bian, et al. · Molecular Cell · 170

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KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9

2010 · X Wang, H Lu, et al. · Oncogene · 163

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Human Kruppel-like Factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription

2000 · J. v. Vliet, J. Turner, et al. · Nucleic Acids Research · 158

DNA Methylation Signatures for Prediction of Biochemical Recurrence After Radical Prostatectomy of Clinically Localized Prostate Cancer

2013 · Christa Haldrup, Kamilla Mundbjerg, et al. · Journal of Clinical Oncology · 127

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A Network of Krüppel-like Factors (Klfs)

2008 · Sally A. Eaton, Alister P.W. Funnell, et al. · Journal of Biological Chemistry · 114

KLF8 transcription factor participates in oncogenic transformation

2006 · X Wang, J Zhao · Oncogene · 106

KLF8 involves in TGF-beta-induced EMT and promotes invasion and migration in gastric cancer cells

2013 · Hui Zhang, Hui Zhang, et al. · Journal of Cancer Research and Clinical Oncology · 103

Up-regulation of Krüppel-Like Factor 8 Promotes Tumor Invasion and Indicates Poor Prognosis for Hepatocellular Carcinoma

2010 · Jia–Chu Li, Xin–Rong Yang, et al. · Gastroenterology · 101

Diverse pathways of epithelial mesenchymal transition related with cancer progression and metastasis and potential effects of endocrine disrupting chemicals on epithelial mesenchymal transition process

2016 · Hae-Miru Lee, Kyung-A Hwang, et al. · Molecular and Cellular Endocrinology · 93

MiR-135a inhibits migration and invasion and regulates EMT-related marker genes by targeting KLF8 in lung cancer cells

2015 · Hongyang Shi, Yuqiang Ji, et al. · Biochemical and Biophysical Research Communications · 82

Sumoylation Delimits KLF8 Transcriptional Activity Associated with the Cell Cycle Regulation

2006 · Huijun Wei, Xianhui Wang, et al. · Journal of Biological Chemistry · 80

Activation of KLF8 Transcription by Focal Adhesion Kinase in Human Ovarian Epithelial and Cancer Cells

2008 · Xianhui Wang, Alison M. Urvalek, et al. · Journal of Biological Chemistry · 70

A functional screen for Krüppel-like factors that regulate the human γ-globin gene through the CACCC promoter element

2005 · Ping Zhang, Priyadarshi Basu, et al. · Blood Cells Molecules and Diseases · 65

KLF8 is associated with poor prognosis and regulates glycolysis by targeting GLUT4 in gastric cancer

2019 · Anwei Mao, Xiang Zhou, et al. · Journal of Cellular and Molecular Medicine · 63

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KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancer

2013 · H Lu, L Hu, et al. · Oncogene · 61

CtBP2 Promotes Human Cancer Cell Migration by Transcriptional Activation of Tiam1

2012 · S. Paliwal, N. Ho, et al. · Genes & Cancer · 60

O-GlcNAc Transferase Regulates Cancer Stem–like Potential of Breast Cancer Cells

2020 · Neha M. Akella, Giang Le Minh, et al. · Molecular Cancer Research · 58

Epithelial–mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cells

2013 · Song-Ze Ding, Yu-Xiu Yang, et al. · Toxicology and Applied Pharmacology · 56

Works count: 254

Citation count: 6,241