Keyword

lecithin:cholesterol acyltransferase

Description: Lecithin:cholesterol acyltransferase is an enzyme that esterifies cholesterol in high-density lipoproteins and contributes to cholesterol transport in the body.

Primary topic: Cholesterol and Lipid Metabolism (55%)

Wikidata ID: wiki/Q14905444

OpenAlex ID: keywords/lcat

The plasma lecithin:cholesterol acyltransferase reaction

1968 · John A. Glomset · Journal of Lipid Research · 2,405

Common variants at 30 loci contribute to polygenic dyslipidemia

2008 · Sekar Kathiresan, Cristen J Willer, et al. · Nature Genetics · 1,363

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

2004 · Jonathan C. Cohen, Robert S. Kiss, et al. · Science · 1,109

Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants

2000 · Anders Dahlqvist, Ulf Ståhl, et al. · Proceedings of the National Academy of Sciences · 882

A protein cofactor of lecithin:Cholesterol acyltransferase

1972 · C.J. Fielding, V.G. Shore, et al. · Biochemical and Biophysical Research Communications · 724

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

2008 · Daniel J. Rader, Eric T. Alexander, et al. · Journal of Lipid Research · 597

Determination of Lecithin: Cholesterol Acyltransfer in Human Blood Plasma

1971 · K. T. Stokke, K. R. Norum · Scandinavian Journal of Clinical and Laboratory Investigation · 554

Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential consequences

2006 · N. D. Vaziri · American Journal of Physiology-Renal Physiology · 541

Mechanisms and consequences of cellular cholesterol exchange and transfer

1987 · Michael C. Phillips, William J. Johnson, et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · 541

Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver.

1976 · R L Hamilton, M C Williams, et al. · Journal of Clinical Investigation · 537

The Metabolic Role of Lecithin: Cholesterol Acyltransferase: Perspectives from Pathology

1973 · JOHN A. GLOMSET, KAARE R. NORUM · Advances in lipid research · 473

A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family.

1980 · G Franceschini, C R Sirtori, et al. · Journal of Clinical Investigation · 472

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Characterization of lipoprotein particles isolated by immunoaffinity chromatography. Particles containing A-I and A-II and particles containing A-I but no A-II.

1984 · M C Cheung, J J Albers · Journal of Biological Chemistry · 471

Lecithin cholesterol acyltransferase

2000 · A Jonas · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 466

A molecular membrane model of sperm capacitation and the acrosome reaction of mammalian spermatozoa

1985 · Jean Langlais, Kenneth D. Roberts · Gamete Research · 424

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Hepatocyte nuclear factor-1α is an essential regulator of bile acid and plasma cholesterol metabolism

2001 · David Q. Shih, Markus Bussen, et al. · Nature Genetics · 422

HDL, its enzymes and its potential to influence lipid peroxidation

1995 · Michael I. Mackness, Paul N. Durrington · Atherosclerosis · 418

Infection and Inflammation‐Induced Proatherogenic Changes of Lipoproteins

2000 · Weerapan Khovidhunkit,, Riaz A. Memon, et al. · The Journal of Infectious Diseases · 403

Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin. Cholesterol acyltransferase

1975 · Anne K. Soutar, Charles W. Garner, et al. · Biochemistry · 392

Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL

2006 · Vassilis I. Zannis, Angeliki Chroni, et al. · Journal of Molecular Medicine · 391

The molecular pathology of lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes

1997 · J A Kuivenhoven, H Pritchard, et al. · Journal of Lipid Research · 367

Cloning and sequencing of human cholesteryl ester transfer protein cDNA

1987 · Dennis Drayna, Alisha Stephens Jarnagin, et al. · Nature · 350

Activation of lecithin: cholesterol acyltransferase by human apolipoprotein A-IV.

1985 · A Steinmetz, G Utermann · Journal of Biological Chemistry · 341

High-density lipoprotein heterogeneity and function in reverse cholesterol transport

2010 · George H Rothblat, Michael C Phillips · Current Opinion in Lipidology · 340

Reverse cholesterol transport and cholesterol efflux in atherosclerosis

2005 · R. Ohashi, H. Mu, et al. · QJM · 336

Works count: 4,296

Citation count: 115,400