Keyword

limb development

Description: The biological process through which animal limbs form and grow into mature structures, involving genetic and signaling mechanisms.

Primary topic: Developmental Biology and Gene Regulation (43%)

Wikidata ID: wiki/Q2277862

OpenAlex ID: keywords/limb-development

Developing human : clinically oriented embryology

1973 · Keith L. Moore, T. V. N. Persaud, et al. · UCLA - Biblioteca de Ciencias de la Salud · 2,303

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1999 · Annie Yang, Ronen Schweitzer, et al. · Nature · 2,225

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

1996 · Andrea Vortkamp, Kaechoong Lee, et al. · Science · 1,995

The FGF family: biology, pathophysiology and therapy

2009 · Andrew Beenken, Moosa Mohammadi · Nature Reviews Drug Discovery · 1,941

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

2002 · Haruhiko Akiyama, Marie-Christine Chaboissier, et al. · Genes & Development · 1,721

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ChIP-seq accurately predicts tissue-specific activity of enhancers

2009 · Axel Visel, Matthew J. Blow, et al. · Nature · 1,640

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Fgf10 is essential for limb and lung formation

1999 · Keisuke Sekine, Hideyo Ohuchi, et al. · Nature Genetics · 1,231

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

1997 · Craig T. Basson, David R. Bachinsky, et al. · Nature Genetics · 1,093

The control of chondrogenesis

2005 · Mary B. Goldring, Kaneyuki Tsuchimochi, et al. · Journal of Cellular Biochemistry · 1,061

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Function and biological roles of the Dickkopf family of Wnt modulators

2006 · C Niehrs · Oncogene · 995

A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo

1999 · Terry P. Yamaguchi, Allan Bradley, et al. · Development · 971

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 · Christina Thaller, Gregor Eichele · Nature · 953

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

2002 · David M. Ornitz, Pierre J. Marie · Genes & Development · 905

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Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

1998 · Hosung Min, Dimitry M. Danilenko, et al. · Genes & Development · 879

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Pattern Regulation in Epimorphic Fields

1976 · Vernon French, Peter J. Bryant, et al. · Science · 866

An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis

2000 · Laurence De Moerlooze, Bradley Spencer-Dene, et al. · Development · 864

Limb alterations in brachypodism mice due to mutations in a new member of the TGFβ-superfamily

1994 · Elaine E. Storm, Thanh V. Huynh, et al. · Nature · 854

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

1991 · Luigi M. De Luca · The FASEB Journal · 843

Pax9 -deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities

1998 · Heiko Peters, Annette Neubüser, et al. · Genes & Development · 833

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Cellular interactions and signaling in cartilage development

2000 · A.M. DeLise, L. Fischer, et al. · Osteoarthritis and Cartilage · 794

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

2012 · Jean-Baptiste Rivière, Ghayda M Mirzaa, et al. · Nature Genetics · 742

Dorsalizing signal Wnt-7a required for normal polarity of D–V and A–P axes of mouse limb

1995 · Brian A. Parr, Andrew P. McMahon · Nature · 726

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation

2003 · Lilia Topol, Xueyuan Jiang, et al. · The Journal of Cell Biology · 724

The Genetics of Hand Malformations

1979 · Margretta R. Seashore · Europe PMC (PubMed Central) · 707

A mouse model of Greig cephalo–polysyndactyly syndrome: the extra–toesJ mutation contains an intragenic deletion of the Gli3 gene

1993 · Chi-chung Hui, Alexandra L. Joyner · Nature Genetics · 706

Works count: 5,976

Citation count: 202,400