Keyword

malin

Description: The titles concern Lafora disease and its genes but do not clarify whether “malin” denotes the EPM2B protein, gene, or disease context.

Primary topic: Glycogen Storage Diseases and Myoclonus (68%)

OpenAlex ID: keywords/malin

Glycogen metabolism in humans

2016 · María M. Adeva-Andany, Manuel González-Lucán, et al. · BBA Clinical · 502

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Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy

2007 · David Vilchez, Susana Ros, et al. · Nature Neuroscience · 377

Mutations in NHLRC1 cause progressive myoclonus epilepsy

2003 · Elayne M Chan, Edwin J Young, et al. · Nature Genetics · 327

Insights into Lafora disease: Malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

2005 · Matthew S. Gentry, Carolyn A. Worby, et al. · Proceedings of the National Academy of Sciences · 238

Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease

2014 · J. Duran, A. Gruart, et al. · Human Molecular Genetics · 181

Lafora disease — from pathogenesis to treatment strategies

2018 · Felix Nitschke, Saija J. Ahonen, et al. · Nature Reviews Neurology · 167

Malin Decreases Glycogen Accumulation by Promoting the Degradation of Protein Targeting to Glycogen (PTG)

2007 · Carolyn A. Worby, Matthew S. Gentry, et al. · Journal of Biological Chemistry · 161

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Lafora disease

2016 · Julie Turnbull, Erica Tiberia, et al. · Epileptic Disorders · 156

Novel glycogen synthase kinase 3 and ubiquitination pathways in progressive myoclonus epilepsy

2005 · Hannes Lohi, Leonarda Ianzano, et al. · Human Molecular Genetics · 153

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

2011 · Olga Criado, Carmen Aguado, et al. · Human Molecular Genetics · 148

Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway

2007 · Maria Carmen Solaz-Fuster, José Vicente Gimeno-Alcañiz, et al. · Human Molecular Genetics · 145

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Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin

2010 · Anna A. DePaoli-Roach, Vincent S. Tagliabracci, et al. · Journal of Biological Chemistry · 139

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Recent advances in the molecular basis of Lafora’s progressive myoclonus epilepsy

2005 · Subramaniam Ganesh, Rajat Puri, et al. · Journal of Human Genetics · 137

Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease

2011 · Jordi Valles‐Ortega, Jordi Duran, et al. · EMBO Molecular Medicine · 124

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Nuclear Glycogenolysis Modulates Histone Acetylation in Human Non-Small Cell Lung Cancers

2019 · Ramon C. Sun, Vikas V. Dukhande, et al. · Cell Metabolism · 112

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The malin–laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin–proteasome system

2008 · Punitee Garyali, Pratibha Siwach, et al. · Human Molecular Genetics · 109

A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori’s disease

2007 · Alan Cheng, Mei Zhang, et al. · Genes & Development · 97

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Lafora disease offers a unique window into neuronal glycogen metabolism

2018 · Matthew S. Gentry, Joan J. Guinovart, et al. · Journal of Biological Chemistry · 92

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Neuronal glycogen synthesis contributes to physiological aging

2014 · Christopher Sinadinos, Jordi Valles‐Ortega, et al. · Aging Cell · 91

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Early-onset Lafora body disease

2012 · Julie Turnbull, Jean-Marie Girard, et al. · Brain · 90

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Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment

2007 · Shuchi Mittal, Deepti Dubey, et al. · Human Molecular Genetics · 88

PTG protein depletion rescues malin‐deficient Lafora disease in mouse

2014 · Julie Turnbull, Jonathan R. Epp, et al. · Annals of Neurology · 83

Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease

2017 · Felix Nitschke, Mitchell A Sullivan, et al. · EMBO Molecular Medicine · 79

Brain glycogen in health and disease

2015 · Jordi Duran, Joan J. Guinovart · Molecular Aspects of Medicine · 78

Increased Endoplasmic Reticulum Stress and Decreased Proteasomal Function in Lafora Disease Models Lacking the Phosphatase Laforin

2009 · Santiago Vernia, Teresa Rubio, et al. · PLoS ONE · 76

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Works count: 321

Citation count: 6,755