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Keyword

MCT1

Description: Monocarboxylate transporter 1, a membrane protein that transports lactate and other monocarboxylates across cell membranes in physiological and disease contexts.
OpenAlex ID: keywords/mct1
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases
2019 · Daniela Parada Venegas, Marjorie K. De la Fuente, et al. · Frontiers in Immunology · 3,804
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Inhibitory effect of tumor cell–derived lactic acid on human T cells
2007 · Karin Fischer, Petra Hoffmann, et al. · Blood · 1,938
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Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
2011 · Akinobu Suzuki, Sarah A. Stern, et al. · Cell · 1,704
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Oligodendroglia metabolically support axons and contribute to neurodegeneration
2012 · Youngjin Lee, Brett M. Morrison, et al. · Nature · 1,658
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
2008 · Pierre Sonveaux, Frédérique Végran, et al. · Journal of Clinical Investigation · 1,633
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
1999 · Andrew P. HALESTRAP, Nigel T. PRICE · Biochemical Journal · 1,349
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Lactate Metabolism in Human Lung Tumors
2017 · Brandon Faubert, Kevin Y. Li, et al. · Cell · 1,334
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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
2021 · McLane J. Watson, Paolo D. A. Vignali, et al. · Nature · 1,271
The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
2004 · Andrew P. Halestrap, David Meredith · Pflügers Archiv - European Journal of Physiology · 1,058
The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism
2006 · Mohammed S. Ullah, Andrew J. Davies, et al. · Journal of Biological Chemistry · 893
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Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments
2022 · Shogo Kumagai, Shohei Koyama, et al. · Cancer Cell · 885
Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis
2011 · Frédérique Végran, Romain Boidot, et al. · Cancer Research · 815
Supply and Demand in Cerebral Energy Metabolism: The Role of Nutrient Transporters
2007 · Ian A Simpson, Anthony Carruthers, et al. · Journal of Cerebral Blood Flow & Metabolism · 811
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Cell–cell and intracellular lactate shuttles
2009 · George A. Brooks · The Journal of Physiology · 801
Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions
2015 · Robert Haas, Joanne Smith, et al. · PLoS Biology · 778
The SLC16 gene family – Structure, role and regulation in health and disease
2013 · Andrew P. Halestrap · Molecular Aspects of Medicine · 764
Evidence Supporting the Existence of an Activity-Dependent Astrocyte-Neuron Lactate Shuttle
1998 · Luc Pellerin, Giovanni Pellegri, et al. · Developmental Neuroscience · 754
The monocarboxylate transporter family—Role and regulation
2011 · Andrew P. Halestrap, Marieangela C. Wilson · IUBMB Life · 744
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Monocarboxylate transporters in the central nervous system: distribution, regulation and function
2005 · Karin Pierre, Luc Pellerin · Journal of Neurochemistry · 739
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Short-chain fatty acids in diseases
2023 · Dan Zhang, Yong-Ping Jian, et al. · Cell Communication and Signaling · 730
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Thoughts and Utterances: The Pragmatics of Explicit Communication
2003 · Anna Papafragou · Lingua · 725
The monocarboxylate transporter family—Structure and functional characterization
2011 · Andrew P. Halestrap · IUBMB Life · 715
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
2000 · P. Kirk, M.C. Wilson, et al. · The EMBO Journal · 701
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota
2017 · Guolin Li, Cen Xie, et al. · Cell Metabolism · 665
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Monocarboxylate transporters in cancer
2019 · Valéry L. Payen, Erica Mina, et al. · Molecular Metabolism · 648
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Works count: 3,660
Citation count: 131,300
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