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Keyword

MCT4

Description: MCT4, or monocarboxylate transporter 4, is a membrane protein that transports lactate and other monocarboxylates across cell membranes.
Wikidata ID: wiki/Q18033844
OpenAlex ID: keywords/mct4
Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
2011 · Akinobu Suzuki, Sarah A. Stern, et al. · Cell · 1,704
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The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
1999 · Andrew P. HALESTRAP, Nigel T. PRICE · Biochemical Journal · 1,349
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The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
2004 · Andrew P. Halestrap, David Meredith · Pflügers Archiv - European Journal of Physiology · 1,058
The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism
2006 · Mohammed S. Ullah, Andrew J. Davies, et al. · Journal of Biological Chemistry · 893
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Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis
2011 · Frédérique Végran, Romain Boidot, et al. · Cancer Research · 815
The SLC16 gene family – Structure, role and regulation in health and disease
2013 · Andrew P. Halestrap · Molecular Aspects of Medicine · 764
The monocarboxylate transporter family—Role and regulation
2011 · Andrew P. Halestrap, Marieangela C. Wilson · IUBMB Life · 744
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Monocarboxylate transporters in the central nervous system: distribution, regulation and function
2005 · Karin Pierre, Luc Pellerin · Journal of Neurochemistry · 739
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The monocarboxylate transporter family—Structure and functional characterization
2011 · Andrew P. Halestrap · IUBMB Life · 715
Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond
2008 · Vadivel Ganapathy, Muthusamy Thangaraju, et al. · Pharmacology & Therapeutics · 711
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
2000 · P. Kirk, M.C. Wilson, et al. · The EMBO Journal · 701
Monocarboxylate transporters in cancer
2019 · Valéry L. Payen, Erica Mina, et al. · Molecular Metabolism · 648
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Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect
2016 · Iñigo San-Millán, George A. Brooks · Carcinogenesis · 611
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Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
2012 · Tania Fiaschi, Alberto Marini, et al. · Cancer Research · 580
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The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
2000 · Kai-Stefan DIMMER, Björn FRIEDRICH, et al. · Biochemical Journal · 577
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Phosphofructokinase and the Pasteur effect
1962 · Janet V. Passonneau, Oliver H. Lowry · Biochemical and Biophysical Research Communications · 517
RNA interference screen for human genes associated with West Nile virus infection
2008 · Manoj N. Krishnan, Aylwin Ng, et al. · Nature · 516
Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease
2020 · Melanie A. Felmlee, Robert S. Jones, et al. · Pharmacological Reviews · 470
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Lactate transport in skeletal muscle — role and regulation of the monocarboxylate transporter
1999 · Carsten Juel, Andrew P. Halestrap · The Journal of Physiology · 447
CD147 subunit of lactate/H + symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
2011 · Renaud Le Floch, Johanna Chiche, et al. · Proceedings of the National Academy of Sciences · 429
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
2014 · Ubaldo E. Martinez-Outschoorn, Michael P. Lisanti, et al. · Seminars in Cancer Biology · 422
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Multiple Biological Activities of Lactic Acid in Cancer: Influences on Tumor Growth,Angiogenesis and Metastasis
2012 · Suveera Dhup, Rajesh Kumar Dadhich, et al. · Current Pharmaceutical Design · 420
Evidence for a stromal-epithelial “lactate shuttle” in human tumors
2011 · Diana Whitaker-Menezes, Ubaldo E. Martinez-Outschoorn, et al. · Cell Cycle · 412
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Role of Monocarboxylate Transporters in Drug Delivery to the Brain
2014 · Nisha Vijay, Marilyn Morris · Current Pharmaceutical Design · 408
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells
2018 · Don Benjamin, Dimitri Robay, et al. · Cell Reports · 407
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Works count: 1,935
Citation count: 64,040
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