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MEG3
Description:
MEG3 is a long non-coding RNA encoded in humans and studied in gene regulation and disease biology.
Primary topic:
Cancer-related molecular mechanisms research (39%)
Related topics:
Cancer-related molecular mechanisms research (39%),
Genetic Syndromes and Imprinting (12%)
Wikidata ID:
wiki/Q18041809
OpenAlex ID:
keywords/meg3
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
2009
·
Elmar W. Tobi
, L.H. Lumey
, et al.
·
Human Molecular Genetics
·
1,157
PDF
Long Noncoding RNA MALAT1 Regulates Endothelial Cell Function and Vessel Growth
2014
·
Katharina M. Michalik
, Xintian You
, et al.
·
Circulation Research
·
940
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
2008
·
Shuomin
, Zhu
, et al.
·
Acta Scientiarum Naturalium Universitatis Sunyatseni
·
831
MEG3 noncoding RNA: a tumor suppressor
2012
·
Yunli Zhou
, Xun Zhang
, et al.
·
Journal of Molecular Endocrinology
·
717
PDF
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures
2015
·
Tanmoy Mondal
, Santhilal Subhash
, et al.
·
Nature Communications
·
665
PDF
Activation of p53 by MEG3 Non-coding RNA
2007
·
Yunli Zhou
, Ying Zhong
, et al.
·
Journal of Biological Chemistry
·
654
PDF
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
2011
·
C Braconi
, T Kogure
, et al.
·
Oncogene
·
642
PDF
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12
2003
·
Shau-Ping Lin
, Neil Youngson
, et al.
·
Nature Genetics
·
470
A Pituitary-Derived MEG3 Isoform Functions as a Growth Suppressor in Tumor Cells
2003
·
Xun Zhang
, Yunli Zhou
, et al.
·
The Journal of Clinical Endocrinology & Metabolism
·
436
Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression
2013
·
Kai-hua Lu
, Wei Li
, et al.
·
BMC Cancer
·
424
PDF
Pathological classification and molecular genetics of meningiomas
2010
·
Christian Mawrin
, Arie Perry
·
Journal of Neuro-Oncology
·
411
Long non-coding RNAs in Huntington's disease neurodegeneration
2011
·
Rory Johnson
·
Neurobiology of Disease
·
398
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q
2000
·
Naoki Miyoshi
, Hirotaka Wagatsuma
, et al.
·
Genes to Cells
·
385
Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin
2014
·
Syuzo Kaneko
, Roberto Bonasio
, et al.
·
Molecular Cell
·
371
PDF
Inhibition of the Cardiac Fibroblast–Enriched lncRNA Meg3 Prevents Cardiac Fibrosis and Diastolic Dysfunction
2017
·
Maria-Teresa Piccoli
, Shashi Kumar Gupta
, et al.
·
Circulation Research
·
344
PDF
Overexpression of the long non‐coding RNA MEG3 impairs in vitro glioma cell proliferation
2012
·
Pengjun Wang
, Zhongqiao Ren
, et al.
·
Journal of Cellular Biochemistry
·
340
Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines
2015
·
Chu-Fan Mo
, Fang-Chun Wu
, et al.
·
Stem Cell Research & Therapy
·
333
PDF
Maternally Expressed Gene 3, an Imprinted Noncoding RNA Gene, Is Associated with Meningioma Pathogenesis and Progression
2010
·
Xun Zhang
, Roger Gejman
, et al.
·
Cancer Research
·
330
PDF
Newborns of obese parents have altered DNA methylation patterns at imprinted genes
2013
·
A Soubry
, S K Murphy
, et al.
·
International Journal of Obesity
·
326
PDF
Maternally Expressed Gene 3 (MEG3) Noncoding Ribonucleic Acid: Isoform Structure, Expression, and Functions
2009
·
Xun Zhang
, Kimberley Rice
, et al.
·
Endocrinology
·
325
PDF
The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
2009
·
Chris Wallace
, Deborah J Smyth
, et al.
·
Nature Genetics
·
325
PDF
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted
2000
·
Jennifer V. Schmidt
, Paul G. Matteson
, et al.
·
Genes & Development
·
310
PDF
Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer
2021
·
Honglin Yan
, Bin Luo
, et al.
·
International Journal of Biological Sciences
·
305
PDF
Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21
2015
·
Jun Zhang
, Tingting Yao
, et al.
·
Cancer Biology & Therapy
·
305
PDF
Downregulated MEG3 activates autophagy and increases cell proliferation in bladder cancer
2012
·
Liang Ying
, Yiran Huang
, et al.
·
Molecular BioSystems
·
299
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Works count:
1,904
Citation count:
59,940
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