Keyword

microphysiological systems

Description: In vitro cell-culture platforms that mimic aspects of human tissue or organ physiology, often using engineered microfluidic devices for biomedical research and drug development.

Primary topic: 3D Printing in Biomedical Research (51%)

Wikidata ID: wiki/Q7101746

OpenAlex ID: keywords/microphysiological-systems

Organs-on-chips: into the next decade

2020 · Lucie A. Low, Christine Mummery, et al. · Nature Reviews Drug Discovery · 1,018

Bioinspired living structural color hydrogels

2018 · Fanfan Fu, Luoran Shang, et al. · Science Robotics · 588

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Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

2018 · Collin D. Edington, Wen Li Kelly Chen, et al. · Scientific Reports · 478

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Fetal bovine serum (FBS): Past – present – future

2017 · Jan van der Valk · ALTEX · 445

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Cell suspensions from organ rudiments of chick embryos

1952 · Aron Moscona · Experimental Cell Research · 386

New approach methodologies in human regulatory toxicology – Not if, but how and when!

2023 · Sebastian Schmeisser, Andrea Miccoli, et al. · Environment International · 385

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

2017 · Duc T. T. Phan, Xiaolin Wang, et al. · Lab on a Chip · 324

Intestinal barrier dysfunction orchestrates the onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip

2018 · Woojung Shin, Hyun Jung Kim · Proceedings of the National Academy of Sciences · 311

Beyond Polydimethylsiloxane: Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems

2020 · Scott B. Campbell, Qinghua Wu, et al. · ACS Biomaterials Science & Engineering · 298

Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing

2016 · Uwe Marx · ALTEX · 294

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Development of a microphysiological model of human kidney proximal tubule function

2016 · Elijah J. Weber, Alenka Chapron, et al. · Kidney International · 273

A Human Breathing Lung-on-a-Chip

2015 · Dongeun (Dan) Huh · Annals of the American Thoracic Society · 268

Biology-inspired microphysiological systems to advance medicines for patient benefit and animal welfare

2020 · Uwe Marx · ALTEX · 258

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The relevance and potential roles of microphysiological systems in biology and medicine

2014 · John P Wikswo · Experimental Biology and Medicine · 245

Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling

2015 · Hasan Erbil Abaci, Michael L. Shuler · Integrative Biology · 243

Design and demonstration of a pumpless 14 compartment microphysiological system

2016 · Paula G. Miller, Michael L. Shuler · Biotechnology and Bioengineering · 238

Tissue microarrays (TMAs) for high-throughput molecular pathology research

2001 · Antonio Nocito, Juha Kononen, et al. · International Journal of Cancer · 238

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In vitro models replicating the human intestinal epithelium for absorption and metabolism studies: A systematic review

2021 · Arianna Fedi, Chiara Vitale, et al. · Journal of Controlled Release · 229

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Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies

2017 · Nikolaos Tsamandouras, Wen Li Kelly Chen, et al. · The AAPS Journal · 222

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Chip-based human liver–intestine and liver–skin co-cultures – A first step toward systemic repeated dose substance testing in vitro

2015 · Ilka Maschmeyer, Tobias Hasenberg, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 219

Liver ‘organ on a chip’

2017 · Colin H. Beckwitt, Amanda M. Clark, et al. · Experimental Cell Research · 208

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Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

2018 · Sabine U Vorrink, Yitian Zhou, et al. · Toxicological Sciences · 186

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A multi-throughput multi-organ-on-a-chip system on a plate formatted pneumatic pressure-driven medium circulation platform

2017 · T. Satoh, S. Sugiura, et al. · Lab on a Chip · 181

A one-stop microfluidic-based lung cancer organoid culture platform for testing drug sensitivity

2019 · Da Jung Jung, Tae Hoon Shin, et al. · Lab on a Chip · 178

Placental Drug Transport‐on‐a‐Chip: A Microengineered In Vitro Model of Transporter‐Mediated Drug Efflux in the Human Placental Barrier

2017 · Cassidy Blundell, Yoon‐Suk Yi, et al. · Advanced Healthcare Materials · 178

Works count: 1,995

Citation count: 32,000