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Keyword

mitophagy

Description: Mitophagy is the selective autophagic process by which cells degrade and recycle mitochondria, helping maintain mitochondrial quality and cellular health.
Wikidata ID: wiki/Q21837024
OpenAlex ID: keywords/mitophagy
A role for mitochondria in NLRP3 inflammasome activation
2010 · Rongbin Zhou, Amir S. Yazdi, et al. · Nature · 5,565
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 · Sébastien Herzig, Reuben J. Shaw · Nature Reviews Molecular Cell Biology · 4,084
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
2008 · Derek Narendra, Atsushi Tanaka, et al. · The Journal of Cell Biology · 4,008
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Ageing as a risk factor for neurodegenerative disease
2019 · Yujun Hou, Xiuli Dan, et al. · Nature Reviews Neurology · 3,284
Mechanisms of mitophagy
2010 · Richard J. Youle, Derek P. Narendra · Nature Reviews Molecular Cell Biology · 3,261
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
2008 · Gilad Twig, Alvaro Elorza, et al. · The EMBO Journal · 3,078
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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2010 · Derek P. Narendra, Seok Min Jin, et al. · PLoS Biology · 2,931
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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 · Sven Geisler, Kira M. Holmström, et al. · Nature Cell Biology · 2,831
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 · Michael Lazarou, Danielle A. Sliter, et al. · Nature · 2,760
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 · Daniel F. Egan, David B. Shackelford, et al. · Science · 2,586
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 · Alicia M. Pickrell, Richard J. Youle · Neuron · 2,298
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Ubiquitin modifications
2016 · Kirby N Swatek, David Komander · Cell Research · 2,085
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Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
2018 · Sarah Pickles, Pierre Vigié, et al. · Current Biology · 2,062
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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 · Noriyuki Matsuda, Shigeto Sato, et al. · The Journal of Cell Biology · 1,965
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The pathways of mitophagy for quality control and clearance of mitochondria
2012 · G Ashrafi, T L Schwarz · Cell Death and Differentiation · 1,889
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The Role of Oxidative Stress in Parkinson's Disease
2013 · Vera Dias, Eunsung Junn, et al. · Journal of Parkinson s Disease · 1,834
Selective autophagy mediated by autophagic adapter proteins
2011 · Terje Johansen, Trond Lamark · Autophagy · 1,731
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
2019 · Evandro F. Fang, Yujun Hou, et al. · Nature Neuroscience · 1,726
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
2012 · Lei Liu, Du Feng, et al. · Nature Cell Biology · 1,686
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 · Cristofol Vives-Bauza, Chun Zhou, et al. · Proceedings of the National Academy of Sciences · 1,613
Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
2008 · Huafeng Zhang, Marta Bosch-Marce, et al. · Journal of Biological Chemistry · 1,601
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Selective degradation of mitochondria by mitophagy
2007 · Insil Kim, Sara Rodriguez-Enriquez, et al. · Archives of Biochemistry and Biophysics · 1,556
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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
2018 · Konstantinos Palikaras, Eirini Lionaki, et al. · Nature Cell Biology · 1,477
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
2009 · H. Chen, D. C. Chan · Human Molecular Genetics · 1,458
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Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 · Jisun Lee, Samantha Giordano, et al. · Biochemical Journal · 1,438
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Works count: 23,340
Citation count: 745,000
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