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Keyword

mRNA modification

Description: A covalent chemical alteration to one or more nucleotides in messenger RNA, affecting its molecular properties and potentially its processing or translation.
Wikidata ID: wiki/Q21104790
OpenAlex ID: keywords/mrna-modification
Dynamic RNA Modifications in Gene Expression Regulation
2017 · Ian A. Roundtree, Molly E. Evans, et al. · Cell · 3,467
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Post-transcriptional gene regulation by mRNA modifications
2016 · Boxuan Simen Zhao, Ian A. Roundtree, et al. · Nature Reviews Molecular Cell Biology · 2,422
Gene expression regulation mediated through reversible m6A RNA methylation
2014 · Ye Fu, Dan Dominissini, et al. · Nature Reviews Genetics · 1,938
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
2019 · Hailing Shi, Jiangbo Wei, et al. · Molecular Cell · 1,934
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Incorporation of Pseudouridine Into mRNA Yields Superior Nonimmunogenic Vector With Increased Translational Capacity and Biological Stability
2008 · Katalin Karikó, Hiromi Muramatsu, et al. · Molecular Therapy · 1,918
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase
2016 · Zejuan Li, Hengyou Weng, et al. · Cancer Cell · 1,509
HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
2015 · Claudio R. Alarcón, Hani Goodarzi, et al. · Cell · 1,509
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The ancient regulatory-protein family of WD-repeat proteins
1994 · Eva J. Neer, Carl J. Schmidt, et al. · Nature · 1,499
Role of RNA modifications in cancer
2020 · Isaia Barbieri, Tony Kouzarides · Nature reviews. Cancer · 1,314
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
2017 · Ian A Roundtree, Guan-Zheng Luo, et al. · eLife · 1,211
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
2017 · Kathrin Leppek, Rhiju Das, et al. · Nature Reviews Molecular Cell Biology · 946
RNA N 6 -methyladenosine methylation in post-transcriptional gene expression regulation
2015 · Yanan Yue, Jianzhao Liu, et al. · Genes & Development · 922
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A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA
2020 · Sara Zaccara, Samie R. Jaffrey · Cell · 801
N1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
2015 · Oliwia Andries, Séan Mc Cafferty, et al. · Journal of Controlled Release · 696
The expanding snoRNA world
2002 · Jean-Pierre Bachellerie, Jérôme Cavaillé, et al. · Biochimie · 669
MTA Is an Arabidopsis Messenger RNA Adenosine Methylase and Interacts with a Homolog of a Sex-Specific Splicing Factor
2008 · Silin Zhong, Hongying Li, et al. · The Plant Cell · 668
Messenger RNA modifications: Form, distribution, and function
2016 · Wendy V. Gilbert, Tristan A. Bell, et al. · Science · 628
Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA
1971 · J. E. Darnell, L. Philipson, et al. · Science · 563
Unique features of the m6A methylome in Arabidopsis thaliana
2014 · Guan-Zheng Luo, Alice MacQueen, et al. · Nature Communications · 474
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Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines
2021 · Kellie D. Nance, Jordan L. Meier · ACS Central Science · 462
Drought stress adaptation: metabolic adjustment and regulation of gene expression
2012 · Sujata Bhargava, Kshitija Sawant · Plant Breeding · 458
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m 6 A in mRNA: An Ancient Mechanism for Fine-Tuning Gene Expression
2017 · Jean-Yves Roignant, Matthias Soller · Trends in Genetics · 426
Reversible RNA adenosine methylation in biological regulation
2012 · Guifang Jia, Ye Fu, et al. · Trends in Genetics · 424
The challenge and prospect of mRNA therapeutics landscape
2020 · Yuhua Weng, Chunhui Li, et al. · Biotechnology Advances · 416
m6A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
2019 · Yuanhui Mao, Leiming Dong, et al. · Nature Communications · 396
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Works count: 921
Citation count: 51,630
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